Term Information

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Accession
GO:0044027
Name
negative regulation of gene expression via chromosomal CpG island methylation
Ontology
biological_process
Synonyms
DNA hypermethylation of CpG island, epigenetic regulation of gene expression via CpG island hypermethylation, hypermethylation of CpG island, negative regulation of gene expression via CpG island hypermethylation, negative regulation of gene expression via chromosomal CpG dinucleotide methylation, negative regulation of gene expression via chromosomal DNA cytosine methylation, DNA hypermethylation of CG island, negative regulation of gene expression via CpG island methylation, negative regulation of gene expression via chromosomal CG dinucleotide methylation, maintenance of DNA methylation
Alternate IDs
None
Definition
An epigenetic gene regulation mechanism that negatively regulates gene expression by methylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide associated with the transcription start site of genes. Source: Wikipedia:Cpg_island, PMID:11898023
Comment
None
History
See term history for GO:0044027 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of negative regulation of gene expression via chromosomal CpG island methylation (GO:0044027)
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negative regulation of gene expression via chromosomal CpG island methylation [is_a relation] is_a  negative regulation of gene expression, epigenetic (GO:0045814)

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