Abstract
The spatial structure of mefenamic acid molecule is investigated by the 2D NOESY method in scCO2 with DMSO. The results will be used to determine the optimal parameters of state for the micronization processing by the GAS technique.





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Funding
This study was financially supported by the Ministry of Education and Science of the Russian Federation (contract nos. 01201260481 and 0120095082), by the Russian Foundation for Basic Research (grant nos. 18-29-06008 and 20-43-370011), and the Council for Grants of the President of the Russian Federation (project MK-662.2021.1.3). The NMR spectroscopy experiment was performed using the molecular fluid spectroscopy facility (http://www.ckp-rf.ru/usu/503933/) of the Krestov Institute of Solution Chemistry of the Russian Academy of Sciences.
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Belov, K.V., Batista de Carvalho, L.A., Dyshin, A.A. et al. Conformational Analysis of Mefenamic Acid in scCO2-DMSO by the 2D NOESY Method. Russ. J. Phys. Chem. B 16, 1191–1199 (2022). https://doi.org/10.1134/S1990793122070028
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DOI: https://doi.org/10.1134/S1990793122070028