Emotion, decision making and the orbitofrontal cortex
- PMID: 10731224
- DOI: 10.1093/cercor/10.3.295
Emotion, decision making and the orbitofrontal cortex
Abstract
The somatic marker hypothesis provides a systems-level neuroanatomical and cognitive framework for decision making and the influence on it by emotion. The key idea of this hypothesis is that decision making is a process that is influenced by marker signals that arise in bioregulatory processes, including those that express themselves in emotions and feelings. This influence can occur at multiple levels of operation, some of which occur consciously and some of which occur non-consciously. Here we review studies that confirm various predictions from the hypothesis. The orbitofrontal cortex represents one critical structure in a neural system subserving decision making. Decision making is not mediated by the orbitofrontal cortex alone, but arises from large-scale systems that include other cortical and subcortical components. Such structures include the amygdala, the somatosensory/insular cortices and the peripheral nervous system. Here we focus only on the role of the orbitofrontal cortex in decision making and emotional processing, and the relationship between emotion, decision making and other cognitive functions of the frontal lobe, namely working memory.
Similar articles
-
The role of emotion in decision-making: evidence from neurological patients with orbitofrontal damage.Brain Cogn. 2004 Jun;55(1):30-40. doi: 10.1016/j.bandc.2003.04.001. Brain Cogn. 2004. PMID: 15134841 Review.
-
The orbitofrontal cortex and beyond: from affect to decision-making.Prog Neurobiol. 2008 Nov;86(3):216-44. doi: 10.1016/j.pneurobio.2008.09.001. Epub 2008 Sep 7. Prog Neurobiol. 2008. PMID: 18824074 Review.
-
Controlling the integration of emotion and cognition: the role of frontal cortex in distinguishing helpful from hurtful emotional information.Psychol Sci. 2006 May;17(5):448-53. doi: 10.1111/j.1467-9280.2006.01726.x. Psychol Sci. 2006. PMID: 16683934
-
The somatic marker hypothesis and the possible functions of the prefrontal cortex.Philos Trans R Soc Lond B Biol Sci. 1996 Oct 29;351(1346):1413-20. doi: 10.1098/rstb.1996.0125. Philos Trans R Soc Lond B Biol Sci. 1996. PMID: 8941953 Review.
-
Role of the amygdala in decision-making.Ann N Y Acad Sci. 2003 Apr;985:356-69. doi: 10.1111/j.1749-6632.2003.tb07094.x. Ann N Y Acad Sci. 2003. PMID: 12724171 Review.
Cited by
-
Activation of cannabinoid system in anterior cingulate cortex and orbitofrontal cortex modulates cost-benefit decision making.Psychopharmacology (Berl). 2015 Jun;232(12):2097-112. doi: 10.1007/s00213-014-3841-6. Epub 2014 Dec 23. Psychopharmacology (Berl). 2015. PMID: 25529106
-
The social-sensory interface: category interactions in person perception.Front Integr Neurosci. 2012 Oct 17;6:81. doi: 10.3389/fnint.2012.00081. eCollection 2012. Front Integr Neurosci. 2012. PMID: 23087622 Free PMC article.
-
Interoceptive awareness in a clinical setting: the need to bring interoceptive perspectives into clinical evaluation.Front Psychol. 2024 Jun 12;15:1244701. doi: 10.3389/fpsyg.2024.1244701. eCollection 2024. Front Psychol. 2024. PMID: 38933585 Free PMC article. Review.
-
Association of Epigenetic Metrics of Biological Age With Cortical Thickness.JAMA Netw Open. 2020 Sep 1;3(9):e2015428. doi: 10.1001/jamanetworkopen.2020.15428. JAMA Netw Open. 2020. PMID: 32926115 Free PMC article.
-
Beyond the Paleolithic prescription: incorporating diversity and flexibility in the study of human diet evolution.Nutr Rev. 2013 Aug;71(8):501-10. doi: 10.1111/nure.12039. Epub 2013 Jun 25. Nutr Rev. 2013. PMID: 23865796 Free PMC article. Review.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
