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. 2009 Jan;37(Database issue):D555-9.
doi: 10.1093/nar/gkn788. Epub 2008 Oct 23.

FlyBase: enhancing Drosophila Gene Ontology annotations

Susan Tweedie  1 , Michael Ashburner, Kathleen Falls, Paul Leyland, Peter McQuilton, Steven Marygold, Gillian Millburn, David Osumi-Sutherland, Andrew Schroeder, Ruth Seal, Haiyan Zhang; FlyBase Consortium
Collaborators, Affiliations

FlyBase: enhancing Drosophila Gene Ontology annotations

Susan Tweedie et al. Nucleic Acids Res. 2009 Jan.

Abstract

FlyBase (http://flybase.org) is a database of Drosophila genetic and genomic information. Gene Ontology (GO) terms are used to describe three attributes of wild-type gene products: their molecular function, the biological processes in which they play a role, and their subcellular location. This article describes recent changes to the FlyBase GO annotation strategy that are improving the quality of the GO annotation data. Many of these changes stem from our participation in the GO Reference Genome Annotation Project--a multi-database collaboration producing comprehensive GO annotation sets for 12 diverse species.

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Figures

Figure 1.
Figure 1.
GO annotation on the Gene Report of D. melanogaster MBD-like gene. Note the presence of contradictory experimental evidence for the term ‘methyl-CpG binding’ as indicated by the use of the qualifier ‘NOT’ for some publications. Each highlighted term links to a CV term report that includes a definition for the term and a diagram indicating its relationship to other terms.
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