doi: 10.1002/eji.200839050.
Human Th17 cells: are they different from murine Th17 cells?
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- PMID: 19283714
- DOI: 10.1002/eji.200839050
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Human Th17 cells: are they different from murine Th17 cells?
Eur J Immunol.
2009 Mar.
Free article
Abstract
Type 17 Th (Th17) cells have been identified as a distinct population of CD4(+) effector T cells different from Th1 and Th2 cells. While the pre-eminent cytokine of Th1 cells is IFN-gamma and that of Th2 cells is IL-4, the distinctive cytokine of Th17 cells is IL-17A. However, although murine and human Th1 and Th2 cells exhibit strong similarities, human and murine Th17 cells seem to differ in several aspects.
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