doi: 10.1507/endocrj.42.767.
Serum insulin-like growth factor-I (IGF-I) in normal Japanese adults
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- PMID: 8822318
- DOI: 10.1507/endocrj.42.767
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Serum insulin-like growth factor-I (IGF-I) in normal Japanese adults
Endocr J.
1995 Dec.
Free article
Abstract
To evaluate surgical and medical treatment of GH-producing pituitary tumors and GH supplement to GH-deficient patients, we determined the reference values for serum IGF-I in Japanese adults. The serum IGF-I concentration in 454 apparently healthy subjects (246 men aged 21-70 years and 208 women aged 21-72 years) was measured with a commercial RIA kit after acid-ethanol extraction. The concentration of serum IGF-I decreased with age in both sexes. The IGF-I in females was significantly higher than that in males in the group aged 21-30 years and lower in the group aged 61-72 years. We conclude that an age- or sex-related standard is necessary for comparing IGF-I values in patients.
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