Somatic cell nuclear transfer
Abstract
Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.
- Publication:
-
Nature
- Pub Date:
- October 2002
- DOI:
- Bibcode:
- 2002Natur.419..583W