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Disease Ontology Browser
IgA glomerulonephritis (DOID:2986)
Alliance: disease page
Synonyms: Berger's IgA or IgG nephropathy; Focal Glomerulonephritis; IgA nephropathy; primary IgA nephropathy; segmental glomerulonephritis
Alt IDs: OMIM:161950, EFO:0004194, MESH:D005922, NCI:C34643, UMLS_CUI:C0017661
Definition: A glomerulonephritis characterized by build up of IgA antibody in the glomerulus.

Disease References using Mouse Models (6)
Mouse Models
Human Disease Modeled: IgA glomerulonephritis
Associated Mouse Gene: Scgb1a1

Allelic Composition Genetic Background Reference Phenotypes
Scgb1a1tm1Abm/Scgb1a1tm1Abm
 involves: 129S1/Sv * 129X1/SvJ J:57504 View
Tg(MMTV-Scgb1a1)#Abm/0
 involves: C57BL/6 * SJL J:57504 View
Mouse Models
Human Disease Modeled: IgA glomerulonephritis
Associated Mouse Gene: B4galt1

Allelic Composition Genetic Background Reference Phenotypes
B4galt1tm1Yiw/B4galt1tm1Yiw
 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:117891 View
Mouse Models
Human Disease Modeled: IgA glomerulonephritis
Associated Mouse Gene: Tnfsf13b

Allelic Composition Genetic Background Reference Phenotypes
Tg(Tnfsf13b)1Fma/Tg(Tnfsf13b)1Fma
 involves: C57BL/6 * DBA/2 J:178227 View
Mouse Models
Human Disease Modeled: IgA glomerulonephritis
Associated Mouse Gene: Tnfsf14

Allelic Composition Genetic Background Reference Phenotypes
Tg(Lck-Tnfsf14)24Yxf/?
 C57BL/6-Tg(Lck-Tnfsf14)24Yxf J:128976 View
Mouse Models
Human Disease Modeled: IgA glomerulonephritis
Associated Mouse Gene: Was

Allelic Composition Genetic Background Reference Phenotypes
Wastm1Sbs/Wastm1Sbs
 129S6/SvEvTac-Wastm1Sbs/J J:180407 View
Mouse Models
Human Disease Modeled: IgA glomerulonephritis
Associated Mouse Transgene: Tg(Itgam-FCAR)83Rcmo

Allelic Composition Genetic Background Reference Phenotypes
Tg(Itgam-FCAR)83Rcmo/0
 involves: C57BL/6 * NOD J:120534 View
Mouse Models
Human Disease Modeled: IgA glomerulonephritis
Associated Mouse Transgene: Tg(Lck-Tnfsf14)24Yxf

Allelic Composition Genetic Background Reference Phenotypes
Tg(Lck-Tnfsf14)24Yxf/?
 C57BL/6-Tg(Lck-Tnfsf14)24Yxf J:128976 View
Mouse Models
Human Disease Modeled: IgA glomerulonephritis
Associated Mouse Transgene: Tg(MMTV-Scgb1a1)#Abm

Allelic Composition Genetic Background Reference Phenotypes
Tg(MMTV-Scgb1a1)#Abm/0
 involves: C57BL/6 * SJL J:57504 View
Mouse Models
Human Disease Modeled: IgA glomerulonephritis
Associated Mouse Transgene: Tg(Tnfsf13b)1Fma

Allelic Composition Genetic Background Reference Phenotypes
Tg(Tnfsf13b)1Fma/Tg(Tnfsf13b)1Fma
 involves: C57BL/6 * DBA/2 J:178227 View
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory