Nature

Cancer fighting CAR-T cells show promising results for hard-to-treat tumours

Trial in China is one of the first times the immune therapy has worked against solid tumours.

NIH grant cuts will axe clinical trials abroad â€” and could leave thousands without care

US agencyâ€™s new policy could abruptly end studies of infectious diseases and cancer, leaving researchers scrambling for funds.

Max Kozlov
News30 May 2025
Black Death bacterium has become less lethal after genetic tweak

Reducing the number of copies of one gene in the pathogen could also make it more transmissible.

Rachel Fieldhouse
News29 May 2025
Global dominance of seasonality in shaping lake-surface-extent dynamics

Monthly mapping of multisource remote-sensing data for 1.4 million lakes reveals that seasonality is the dominant driver of lake-surface-extent variations globally.

Luoqi Li
Di Long
R. Iestyn Woolway
Article28 May 2025
Daily briefing: The sweet smell of outer space

How the smells of outer space could lead us to extraterrestrial life. Plus, an ancient â€˜ambidextrousâ€™ protein that can function in both mirror-image forms and the monthâ€™s best science images.

Jacob Smith
Nature Briefing30 May 2025
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Current Issue29 May 2025

News & Comment

How do I choose a principal investigator for my next postdoc?

A computer scientist is struggling to trust their postdoctoral research adviser after negative experiences with the previous two. How do you find one thatâ€™s right for you?

Nikki Forrester

Career Feature02 Jun 2025
How to keep astronauts healthy in deep space
Farhan M. Asrar

Comment02 Jun 2025
The polar regions hold crucial scientific secrets â€” and the time to study them is running out
Marc Macias-Fauria

Book Review02 Jun 2025
Cancer-fighting CAR T cells show promising results for hard-to-treat tumours
Rachel Fieldhouse

News02 Jun 2025
Web-scraping AI bots cause disruption for scientific databases and journals
Diana Kwon

News02 Jun 2025
Rare â€˜ambidextrousâ€™ protein breaks rules of handedness
Ewen Callaway

News02 Jun 2025
Gender equality in research publishing is a responsibility for everyone

Editorial30 May 2025

Latest Reviews & Analysis

- Underwater kelp forests are losing a turf war
  
  In warming coastal seas, a crucial ecosystem is being replaced by â€˜turfsâ€™ of red algae, which release chemicals that suppress kelp survival.
  
  Holly Smith
  
  News & Views30 May 2025
- Origins of the â€˜vampire fungusâ€™ that causes white-nose syndrome in bats
  
  An emerging fungal infection is endangering bats in America. DNA analysis reveals that the infection first arose in Europe, mediated by two fungal culprits.
  
  Matthew C. Fisher
  
  News & Views28 May 2025
- Reverse electron transport drives metabolic changes in obesity
  
  Mitochondria, best known for converting nutrients into energy, also generate superoxide and hydrogen peroxide â€” redox signalling molecules that become harmful when overproduced. Research reveals that such overproduction is not random, but rather occurs at a specific site in one mitochondrial enzyme, opening the door to targeted therapies for metabolic diseases.
  
  Research Briefing28 May 2025
- Light reflects as a vortex off a metamaterial with unusual optical properties
  
  Metamaterials made of magnetic photonic crystals have been generated and tuned to a theoretically predicted transition point at which peculiar optical properties emerge. For example, when light is shone on a slab of the material, some of it is reflected back as a spatio-temporal vortex.
  
  Research Briefing28 May 2025
- Shifting research focus comes with the risk of reduced impact
  
  An analysis of millions of scientific papers and patents shows that the further a researcher or inventor moves from their previous work, the less cited their latest work will be.
  
  StaÅ¡a MilojeviÄ‡
  
  News & Views28 May 2025
- Molecular blueprint of a cellular sorting centre
  
  Research Briefing28 May 2025
- The shaping of terrestrial planets by late accretions
  
  Simone Marchi
  Jun Korenaga
  
  Review Article28 May 2025
- The history and future of resting-state functional magnetic resonance imaging
  
  Bharat B. Biswal
  Lucina Q. Uddin
  
  Review Article28 May 2025
- The diet crazes of the nineteenth century
  
  News & Views27 May 2025

Latest Research articles

Mouse liver assembloids model periportal architecture and biliary fibrosis

Anna M. Dowbaj
Aleksandra Sljukic
Meritxell Huch
Article29 May 2025
Electricity-driven enzymatic dynamic kinetic oxidation

Beibei Zhao
Yuanyuan Xu
Xiaoqiang Huang
Article28 May 2025
Protein-primed homopolymer synthesis by an antiviral reverse transcriptase

Stephen Tang
RimantÄ— Å½edaveinytÄ—
Samuel H. Sternberg
Article28 May 2025
Pt migration-lockup in zeolite for stable propane dehydrogenation catalyst

Zhikang Xu
Mingbin Gao
Xiaojun Bao
Article28 May 2025
Cross-tissue multicellular coordination and its rewiring in cancer

Comprehensive single-cell transcriptomic analysis of 35 human tissues reveals 12 cross-tissue coordinated cellular modules that exhibit intramodule communication and dynamic changes with ageing, and whose organization is perturbed during cancer progression.

Qiang Shi
Yihan Chen
Zemin Zhang
ArticleOpen Access28 May 2025

Since US President Donald Trump took office in January 2025, his team has made major changes to the federal government that have disrupted research and research institutions in the United States and beyond.

Collection 26 Feb 2025

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Tier 2 Canada Research Chair Faculty Position in Supercomputing and High-Performance Computing

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Kingston, Ontario (CA)

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Seeking Excellent Young Scientists Fund (overseas) and academic positions at all levels

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junior professorship position (f/m/d) in Single-Cell Systems Biology

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WÃ¼rzburg (Stadt), Bayern (DE)

Julius-Maximilians-University WÃ¼rzburg - Faculty of Medicine

Cancer fighting CAR-T cells show promising results for hard-to-treat tumours

NIH grant cuts will axe clinical trials abroad â€” and could leave thousands without care

Black Death bacterium has become less lethal after genetic tweak

Global dominance of seasonality in shaping lake-surface-extent dynamics

Daily briefing: The sweet smell of outer space

News & Comment

How do I choose a principal investigator for my next postdoc?

How to keep astronauts healthy in deep space

The polar regions hold crucial scientific secrets â€” and the time to study them is running out

Cancer-fighting CAR T cells show promising results for hard-to-treat tumours

Web-scraping AI bots cause disruption for scientific databases and journals

Rare â€˜ambidextrousâ€™ protein breaks rules of handedness

Gender equality in research publishing is a responsibility for everyone

Latest Reviews & Analysis

Underwater kelp forests are losing a turf war

Origins of the â€˜vampire fungusâ€™ that causes white-nose syndrome in bats

Reverse electron transport drives metabolic changes in obesity

Light reflects as a vortex off a metamaterial with unusual optical properties

Shifting research focus comes with the risk of reduced impact

Molecular blueprint of a cellular sorting centre

The shaping of terrestrial planets by late accretions

The history and future of resting-state functional magnetic resonance imaging

The diet crazes of the nineteenth century

Latest Research articles

Mouse liver assembloids model periportal architecture and biliary fibrosis

Electricity-driven enzymatic dynamic kinetic oxidation

Protein-primed homopolymer synthesis by an antiviral reverse transcriptase

Pt migration-lockup in zeolite for stable propane dehydrogenation catalyst

Cross-tissue multicellular coordination and its rewiring in cancer

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How Trump 2.0 is reshaping science

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Science jobs

Tier 2 Canada Research Chair Faculty Position in Supercomputing and High-Performance Computing

Faculty Positions

Seeking Excellent Young Scientists Fund (overseas) and academic positions at all levels

Faculty Positions

junior professorship position (f/m/d) in Single-Cell Systems Biology

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The origin of vertebrate teeth and evolution of sensory exoskeletons

Ru and W isotope systematics in ocean island basalts reveals core leakage

â€˜Scienticideâ€™ in Argentina sparks huge protest by researchers

Detection of X-ray emission from a bright long-period radio transient

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