Pinnacle Physics Ref Guide
Pinnacle Physics Ref Guide
REFERENCE GUIDE
Release 9
English
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Philips Medical Systems
Pinnacle3 Physics Reference Guide
Document number
4535 604 45211 A
Device description
The Pinnacle3 Radiation Therapy Planning (RTP) software is composed of several modules including the core Pinnacle3
functionality, Syntegra, P3IMRT, P3MD, and AcQSim3. The Pinnacle3 RTP software runs on a Solaris UNIX
operating system or through a UNIX terminal emulation package on a personal computer, which allows qualified medical
personnel to enter patient data into the system, use that data to construct a plan for radiation therapy, and evaluate the
plan. Optionally, the qualified medical personnel may output the plan in an electronic or printed form for use by other
systems in the delivery of treatment to a patient.
Pinnacle3 includes networking capabilities to provide connectivity to other Pinnacle3, Syntegra, P3PC (remote planning),
P3MD, AcQSim3, or P3IMRT workstations, MS Windows-based Web Publishing servers, input devices and output
devices, as well as access to the Pinnacle3 database from any Pinnacle3 workstation available on the network. Networking
connectivity may be via either a local or wide area network.
This software is intended to be user-installable. Installation instructions appear on the CD insert included with the
software CD. You only need to load the software on the system(s) designated as the server(s) at your site. Web Publishing
servers come with the software installed and only need configuration at your site.
To enable use of the software, a licensing key must be issued by a Customer Support representative or your local
distributor. You may contact Customer Support at 1-800-722-9377 (US and Canada) or your local distributor for
assistance with installation or licensing.
Intended use
Pinnacle3 RTP system is a computer software package intended to provide support for radiation therapy treatment
planning for the treatment of benign or malignant disease processes. Pinnacle3 RTP system assists the clinician in
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formulating a treatment plan that maximizes the dose to the treatment volume while minimizing the dose to the
surrounding normal tissues. The system is capable of operating in both the forward planning and inverse planning modes.
The device is indicated for use in patients deemed to be acceptable candidates for radiation treatment in the judgement of
the clinician responsible for patient care. Plans generated using this system are used in the determination of the course of a
patients radiation treatment. They are to be evaluated, modified, and implemented by qualified medical personnel.
Contraindications
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There are no known contraindications regarding the use of the Pinnacle3 RTP system.
Pinnacle 3 Release 9 3
Intended audience
This manual is written for qualified medical personnel trained as users of Pinnacle3 RTP systems. You should make sure
that you have thoroughly read and completely understand the manuals and release notes that are delivered with the
software. Keep this manual and all other manuals delivered with the software near your Pinnacle3 system and review them
periodically. The initial installation procedure will be performed by a Field Service Engineer. If you suspect that your
system has an error, discontinue its use and contact Customer Support or your local distributor.
To assure proper treatment, it is critical that a qualified medical person review and verify all system treatment
plan parameters using an independent verification method prior to treating patients using the plan.
We recommend that you review TG40, TG53, and other pertinent radiation therapy treatment standards and
incorporate those methods into your clinical practice to ensure that your use of the system results in the most
accurate treatment plans. TG40, TG53, and other reports are available publicly at the American Association of
Physicists in Medicine (AAPM) website.
Comprehensive QA for radiation oncology: Report of AAPM Radiation Therapy Committee Task Group 40.
Medical Physics 21(4), 1994.
American Association of Physicists in Medicine Radiation Therapy Committee Task Group 53: Quality
assurance for clinical radiotherapy treatment planning. Medical Physics 25(10), 1998.
The following clinical practices are recommended to verify the accuracy of each treatment plan:
An independent calculation of the monitor units for each beam of a plan and treatment time for each
brachytherapy plan.
Acquisition and review of portal images or review of multi-leaf collimator (MLC) leaf positions after import to
the treatment system.
A chart check prior to the plan being delivered or during the first week of treatment.
Independent review of the treatment plan prior to the delivery.
Cross-functional review of the plan in a weekly chart round.
Manual verification of record and verify settings after transfer to the treatment machine.
Verification of the SSD and field shape during patient setup.
These reviews should be performed for a new plan or when a change is made to any component of a plan.
U.S.A. law: CAUTION: Federal law restricts this device to use by or on the order of a physician.
Only qualified medical personnel should operate the system. New personnel should receive training prior to
unsupervised operation of the system. For more information, contact Customer Support or your local
distributor.
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Serious injury to patients can result due to the misapplication of this product. Make sure that you thoroughly
understand all the user instructions prior to using this device.
Pinnacle3 treatment plans may include the statement NOT FOR CLINICAL USE. Based on the machine or
isotope data and the treatment plan, the software determined that the plan cannot be delivered clinically. Do not
treat patients with plans that are not for clinical use.
Pinnacle3 includes sample data. This information is for reference purposes only. Do not treat patients with plans
based on sample machines or other sample data.
4 Pinnacle 3 Release 9
Contents
1 Introduction ..................................................................................................................... 9
Pinnacle 3 Release 9 5
3.5 Automodeling sequences ........................................................................................ 50
3.5.1 E_TuneAllInSections ................................................................................ 51
3.5.2 FineTuneCrossBeam ................................................................................. 51
3.5.3 FineTuneSpectrum.................................................................................... 51
3.5.4 FineTuneECAndSpectrum........................................................................ 52
3.5.5 FineTuneECInParallel............................................................................... 52
3.5.6 FineTuneECInSections ............................................................................. 52
3.5.7 FineTuneECSequentially........................................................................... 53
3.5.8 FineTuneModelForOpenAndWedgedFields ............................................. 53
3.5.9 FineTuneModifierScatter .......................................................................... 53
3.5.10 FineTuneAllForWedge.............................................................................. 53
3.5.11 FineTuneModelForFieldSize ..................................................................... 54
3.6 Photon beam output factor computation ............................................................... 54
3.6.1 How the software uses output factors ........................................................ 54
3.6.2 Why the softwares scatter factors cannot be measured .............................. 56
3.7 References and recommended reading .................................................................... 58
6 Pinnacle 3 Release 9
6 Brachytherapy Physics .................................................................................................. 85
6.1 Brachytherapy dose calculation ............................................................................... 85
6.1.1 The geometric dose calculation method ..................................................... 85
6.1.2 TG43 dose computation method............................................................... 89
6.2 References and recommended reading .................................................................... 94
8.19 Photon beam measured data worksheet 6: Open field ........................................... 123
8.20 Photon beam measured data worksheet 7: Open field ........................................... 124
8.21 Photon beam measured data worksheet 8: MLC field ........................................... 125
8.22 Photon beam measured data worksheet 9: MLC field ........................................... 126
8.23 Photon beam measured data worksheet 10: MLC field ......................................... 127
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8.24 Photon beam measured data worksheet 11: MLC field ......................................... 128
8.25 Photon beam measured data worksheet 12: MLC field ......................................... 129
8.26 Photon beam output factors worksheet ................................................................. 130
8.27 Wedged field output factors worksheet ................................................................. 131
8.28 Stereotactic radiosurgery energy information ........................................................ 132
8.29 Stereotactic radiosurgery measured data worksheet ............................................... 133
Pinnacle 3 Release 9 7
8.30 Stereotactic radiosurgery output factors worksheet ............................................... 134
8.31 Electron beam energy information ....................................................................... 135
8.32 Electron beam measured data worksheet 1 ........................................................... 136
8.33 Electron beam measured data worksheet 2 ........................................................... 137
8.34 Electron beam measured data worksheet 3 ........................................................... 138
8.35 Electron beam measured data worksheet 4 ........................................................... 139
8.36 Electron beam measured data worksheet 5 ........................................................... 140
8.37 Electron output factors worksheet 1 ..................................................................... 141
8 Pinnacle 3 Release 9
1 Introduction
requirement due to the size of the field width, the software splits the beam.
The beams will be split if the following equation is satisfied:
where FS is the field size along the leaf-travel direction, MTD is the
maximum tip difference allowed by the machine, LG is the minimum
dynamic leaf gap, and LJO is the minimum leaf/jaw overlap.
In some cases, the beams may be required to split even if the field size is
smaller than the maximum tip difference overall. For example, given a
field size of 14 cm, a maximum tip difference of 14.5 cm, a minimum
dynamic leaf gap of 0.05 cm, and a minimum leaf/jaw overlap of 0.5 cm,
the beams would be required to split because the field size is larger than
the maximum tip difference minus the minimum dynamic leaf gap and
the minimum leaf/jaw overlap.
Maximum leaf/jaw
overlap (0.5 cm)
Field size
(12 cm)
Minimum dynamic
leaf gap (0.5 cm)
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Minimum leaf/jaw
overlap (0.2 cm)
Isocenter plane
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Leaf offset
The radius of curvature for the MLC leaves in published literature is about
8 cm for a Varian MLC1, and this is the default in Pinnacle3. The radius of
curvature for Elekta MLC leaves should be approximately 12.2 cm for
Use the Leaf Offset Calibration table in the Rounded Leaf End
Specification window to correct for the difference between the actual leaf
positions and the leaf positions in Pinnacle3. The table shifts the
penumbra based on the leaf positions but does not affect the penumbra
shape. For more information about the offset table, see Graves, et al.2
To model the tongue and groove effect, vary the widths from 0.005 to
0.200 cm and compare the models to the measured profiles. Increasing the
width widens the penumbra in the direction perpendicular to the leaf
motion. Decreasing the width sharpens the penumbra.
MLC leaf front view
Tongue
Groove
Tongue and
groove width
Tongue
Groove
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2.5 References
1 LoSasso T., C. Chui, and C. Ling. 1998. Physical and Dosimetric
Aspects of a Multileaf Collimation System Used in the Dynamic Mode
for Implementing Intensity Modulated Radiotherapy. Medical Physics
25 (10):1919-1927.
2 Graves M., A. Thompson, M. Martel, D. McShan, and B. Fraass.
2001. Calibration and Quality Assurance for Rounded Leaf-end MLC
Systems. Medical Physics 28(11) 2227-2233.
This section describes the photon beam physics dose calculation and the
photon measured data requirements.
WA R N I N G The accuracy of the treatment planning dose calculation depends on the quality of
the data entered in the physics tool. If the quality of this data is poor, or if the
computed dose is not verified with measured data, the dose calculation may be
inaccurate. Please read and follow these instructions carefully.
the field.
Dose profiles extending outside the field for the determination of
scatter dose and jaw transmission from the machine head components.
Various profiles with the MLC aperture to verify dose accuracy for
MLC fields.
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In addition, the following data must be measured for each wedge on each
machine at each energy: depth doses and dose profiles measured with the
wedge in place, and wedged field relative output factors.
N OT E If you have equipment that has the capacity, you can measure profiles and output
factors for field sizes smaller than those recommended in the following sections. You
may need to adjust the dose grids appropriately to fully utilize this data. In general,
you should measure output factors down to the smallest field sizes that you plan to
use clinically.
Y profile Y profile
X profile
+Y offset
Bottom/Top
offset
-Y offset
X profile
-X offset +X offset
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Left/Right offset
Elekta
In order for Pinnacle3 to model the MLC transmission accurately (for
non-Beam Modulator machines), the MLC must be positioned at least
1 cm beyond the backup jaw. The normal operation mode of an Elekta
machine (with the MLC leaves aligned with the backup jaw) makes it
difficult to measure only the jaw transmission or only the MLC
transmission.
Open field data should be collected in the same mode in which the
machine will be used. The MLC-defined fields can be measured in Elekta
Service Mode.
After you have imported the profiles into Pinnacle3, be sure to set the
MLC tracks jaws option to MLC tracks XY jaws for open fields in the
MLC Editor window.
Once you have completed automodeling, adjust the MLC transmission
and the X and Y jaw transmissions as necessary, and then compute dose
and validate your model. The transmission values you enter should
approximate the small-field transmission values that are appropriate for
your machine. The MLC transmission value is the most critical.
If you do not feel comfortable measuring the MLC-defined fields in
Elekta Service Mode, you can approximate the transmission values in the
physics tool. Enter the correct MLC and jaw transmission values prior to
starting automodeling. Once you have completed automodeling, adjust
the MLC transmission and the X and Y jaw transmissions as necessary,
and then compute dose and validate your model.
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Siemens
It is difficult to measure individual transmission values for the jaws and
MLC on the Siemens machines for which the MLC replaces the jaw
because of the way the jaws and MLC work together.
Open field data should be collected in the same mode in which the
machine will be used.
You do not need to measure MLC-defined profiles as described in this
chapter because the open field data allows automodeling of the MLC
transmission.
After you have imported the profiles into Pinnacle3, be sure to set the
MLC tracks jaws option to MLC tracks XY jaws for open fields in the
MLC Editor window. Also, make sure you have the MLC replaces jaws
option set to Yes in the same window.
Once you have completed automodeling, adjust the MLC transmission
and the Y jaw transmission as necessary, and then compute dose and
validate your model. The transmission values you enter should
approximate the small-field transmission values that are appropriate for
your machine. The MLC transmission value is the most critical.
3.2.4 Open field depth dose measurements for energy spectrum and
electron contamination determination
For each energy on each machine, central axis depth dose curves must be
measured using open fields. In the beam modeling process, the depth dose
curves are used to determine the energy spectrum. The setup information
for the depth dose measurements is provided below.
N OT E The measurement resolution (0.20 cm) is a recommended value. Data measured
using higher resolutions may be used, but the calculation time will increase. The use
of lower resolution data (increments of 0.30 cm or greater) can result in poor
models and inaccurate clinical results.
Field Sizes MLC field 2.4 cm x 2.4 cm, 3.2 cm x 3.2 cm, 4.8 cm x 4.8 cm,
(fixed jaw machines) 5.6 cm x 5.6 cm, 8.0 cm x 8.0 cm, 10.4 cm x 10.4 cm,
15.2 cm x 15.2 cm, and the largest possible field size.
N OT E IMRT can involve the use of very small, heavily blocked fields (2 cm x 2 cm or
smaller). Be sure to measure field sizes comparable to those you expect to treat.
Also, if you expect to use very small field sizes defined by the jaws, as opposed to
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the MLC leaves, you should also collect 2 cm x 2 cm and 3 cm x 3 cm PDDs and
profiles.
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10 cm x 10 cm
5 cm x 5 cm
= SAD
(e.g., 100 cm)
Water
surface
Central axis
depth dose
with 0.20 cm
resolution
3.2.5 Measuring dose profiles for incident energy fluence inside field
and outside field
These profiles will be used in adjusting the inside of field fluence and the
outside of field transmission. The measured profiles should extend as far
outside the field boundary as possible.
N OT E The measurement resolution (0.20 cm) is a recommended value. Data measured
using higher resolutions may be used, but the calculation time will increase. The use
of lower resolution data (increments of 0.30 cm or greater) can result in poor
models and inaccurate clinical results.
Field Sizes* MLC field** 2.4 cm x 2.4 cm, 3.2 cm x 3.2 cm, 4.8 cm x 4.8 cm,
(fixed jaw machines) 5.6 cm x 5.6 cm, 8.0 cm x 8.0 cm, 10.4 cm x 10.4 cm,
15.2 cm x 15.2 cm, and the maximum field size
N OT E IMRT can involve the use of very small, heavily blocked fields (2 cm x 2 cm or
smaller). Be sure to measure field sizes comparable to those you expect to treat.
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Also, if you expect to use very small field sizes defined by the jaws, as opposed to
the MLC leaves, you should also collect 2 cm x 2 cm and 3 cm x 3 cm PDDs and
profiles.
N OT E To model more accurately the outer corners of large fields, you may also measure
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one or two additional X and Y profiles for the largest field size. For these profiles,
use a large offset from the central axis. For more information, see Optional profiles
for the corners of a field.
N OT E If you measure MLC field sizes other than those recommended above and you want
to use those measurements for automodeling, make sure the MLC leaves extend
past the jaws by at least 1 cm on one side or the measurements will not be used in
automodeling.
N OT E MLC scans should avoid interleaf leakage and abutted leaf ends. The software
allows you to offset scans and to position closed leaf ends away from the CAX to
avoid these geometries. See the Importing and Entering Measured Beam Data
chapter in the Pinnacle3 Physics Instructions for Use for information.
10cm x 10cm
5cm x 20cm
Water
surface
x
y
Field Sizes MLC field 2.4 cm x 2.4 cm, 3.2 cm x 3.2 cm, 4.8 cm x 4.8 cm,
(fixed jaw machines) 5.6 cm x 5.6 cm, 8.0 cm x 8.0 cm, 10.4 cm x 10.4 cm,
15.2 cm x 15.2 cm, and the maximum field size
N OT E Be sure to measure field sizes comparable to those you expect to treat. Also, if you
expect to use very small field sizes defined by the jaws, as opposed to the MLC
leaves, you should also collect 2 cm x 2 cm and 3 cm x 3 cm PDDs and profiles.
10 cm x 10 cm
5 cm x 5 cm
= SAD
(e.g., 100 cm)
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Water
surface
Central axis
depth dose
with 0.20 cm
resolution
Measurement Type Dose profiles through the central axis in the wedged
direction and the non-wedged direction.
Field Sizes MLC field In the wedged direction, 2.4 cm x 2.4 cm, 3.2 cm x 3.2 cm,
(fixed jaw machines) 4.8 cm x 4.8 cm, 5.6 cm x 5.6 cm, 8.0 cm x 8.0 cm,
10.4 cm x 10.4 cm, 15.2 cm x 15.2 cm, and the maximum
field size.
Depths dmax, 5 cm, 10 cm, and 20 cm. (In the non-wedged direction,
you only need to measure one depth for each field size to
verify the models validity.)
Resolution 0.20 cm
N OT E Be sure to measure field sizes comparable to those you expect to treat. Also, if you
expect to use very small field sizes defined by the jaws, as opposed to the MLC
leaves, you should also collect 2 cm x 2 cm and 3 cm x 3 cm PDDs and profiles.
N OT E To model more accurately the outer corners of large fields, you may also measure
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one or two additional X and Y profiles for the largest field size. For these profiles,
use a large offset from the central axis. For more information, see Optional profiles
for the corners of a field.
= SAD
(e.g., 100 cm)
Water
surface
region:
Contaminant electrons, which scatter off the flattening filter and
collimators, enter the patient and boost the dose in the buildup region.
In Pinnacle3, an exponential function is used to model electron
contamination and this electron dose is added to the photon dose.
WA R N I N G Measuring output factors at dmax (or anywhere within the electron contamination
region for the energy) may result in incorrect monitor unit calculations.
The calibration output factor measurement and the relative output factor
measurements (described in the following section) must be measured
using the same depth.
N OT E Currently, the software requires a 10 cm x 10 cm field size for calibration output
factor measurements. For fixed jaw machines, the field size is defined by the user
and corresponds to an MLC-defined field instead of a jaw-defined field.
OF Information Measurement
The relative output factor for an open field is calculated using the
equation
Dose FS
OF = ------------------
-
Dose CFS
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where DoseFS is the measured dose for the given field size and DoseCFS is the
measured dose for the calibration field.
Field sizes (fixed jaw 2.4 cm x 2.4 cm, 3.2 cm x 3.2 cm, 4.8 cm x 4.8 cm,
machines): 5.6 cm x 5.6 cm, 8.0 cm x 8.0 cm, 10.4 cm x 10.4 cm,
15.2 cm x 15.2 cm, and the maximum field size
20cm x 20cm
10cm x 10cm
= SAD 5cm x 5cm
(e.g., 100 cm)
Water
surface
Calibration
depth
where DoseWFS is the measured dose for the given wedged field size and
DoseCFS is the measured dose for the open calibration field. Note that the
ratio is not the wedge transmission factor because DoseCFS is the fixed open
calibration field dose.
WA R N I N G The wedge transmission factor cannot be substituted for the wedged field output
factors. Using the wedge transmission factor instead of wedged field output factors
will result in incorrect monitor unit calculations.
Field sizes (fixed jaw 2.4 cm x 2.4 cm, 3.2 cm x 3.2 cm, 4.8 cm x 4.8 cm,
machines): 5.6 cm x 5.6 cm, 8 cm x 8 cm, 10.4 cm x 10.4 cm, and
15.2 cm x 15.2 cm, and largest field size possible
Modifiers Wedge
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= SAD
(e.g., 100 cm)
Water
surface
Calibration
depth
CAUTION You should validate your beam models, particularly the output factors for
motorized wedges, by comparing Pinnacle3 calculations with measurements. Use
fields that are similar to those you are likely to treat, and use both square and
rectangular fields. Ideally, this validation should be done before you commission the
machine.
The jaw transmission and head scatter effects are both relatively small;
consequently, they are modeled by a single transmission factor that is
specific to each dynamic wedge and energy. The modulation of the
primary transmission image by this transmission factor is shown below:
When comparing the measured and computed depth dose profiles, you
will increase or decrease the relative number of photons for different
energy bins depending upon the region of the depth dose which needs to
be adjusted. The shape of the depth dose curves is most dependent upon
the relative number of mid-range and high energy photons. The specified
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Electron dose
Depth
EC Surf
dose
Dose
Max Depth
Depth
The Depth Coefficient determines the rate of the electron dose fall-off
with respect to depth. Increasing the Depth Coefficient increases the rate
of fall-off. For example, the figures below show a depth coefficient of
1 and 4.
Depth Effect
F FS ( fs )
----------------
SF
F FS ( fs ) e K d e K MAXD
F Depth ( d, fs ) = ---------------
- ----------------------------------------
K MAXD
-
SF 1e
F Depth ( d, fs )
F FS ( fs )
0
DF MAXD MAXD
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d (Depth) (cm)
The software models this effect using a Gaussian curve (with radial
symmetry). When the Off-Axis Coefficient is set to 0, the Gaussian curve
is flat. As the value increases, the Gaussian curve becomes more narrow,
effectively reducing electron contamination off the central axis.
The EC Field Size Dependence parameters (C1, C2, C3) model the change
in electron contamination as a function of field size. These changes are
generally linear for low energies with increasing curvature at higher
energies. In the software, this effect is modeled using the equation:
C 3 10 C 3 fs
F FS ( fs ) = ECD 10 10 + C 1 ( fs 10 ) + C 2 ( e e )
where
FFS = field size factor
fs = field size
ECD10x10 = Electron Contamination Surface Dose for a 10 x 10 field
C1, C2, C3 = Model parameters fitted to match the measured data
Constraints: C2 > 0
WA R N I N G C1, C2, and C3 are used to produce a function of field size. They should be the same
for each model when the models have been created for each field size.
If you have photon models that are in the same wedge group but have different
field sizes, you cannot assign different values for C1, C2, and C3. It causes problems
in the interpolation over field size for the different field-size specific models and will
prevent commissioning of the machine.
Profile points
automodeled
Shoulder break point
as determined by
Pinnacle3
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Click the Arbitrary Profile Editor button to open the Edit Fluence Filter
Profile window. (This window also appears if you change the Modeled As
option from Cone to Arbitrary Profile.) A default arbitrary fluence profile
is created with 50 points. The profile is generated out to the squared sum
of the largest measurement geometry and increases at 0.6% per cm.
If the arbitrary fluence table is not as wide as the incident energy fluence,
the software extrapolates the table by extending the last value of the table
beyond the maximum position of the table itself to the edges of the
incident fluence.
Use the E_TuneAllInSections sequence to automodel the profile, or use
the Ins After, Ins Before, Delete Point, and Delete All Points buttons to
edit the profile. Arbitrary Profiles can contain from 2 to 200 points.
N OT E For each point in the profile, the radius must be 0 cm50 cm, and the incident
fluence value must be 0.51.5, or you will not be able to compute dose.
Cone model
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When you select Cone from the Modeled As option list, the Fluence
Increase/cm and Cone radius fields appear on the In Field tab. See the
Photon Beam Physics & Physics Utilities chapter in the Pinnacle3
Physics Instructions for Use for information about the cone model.
OffAxisSofteningParam
1
W ' i = W i --------------------------
1 + ----------
Ei
E max
where
Wi = the spectral weight for bin i which has an effective energy Ei
= the off-axis angle
Emax = maximum energy in the beam spectrum
The off-axis angle is calculated in the following way:
= atan -------------------------------
OffAxisDist
SAD
where OffAxisDist is the distance from the central axis in the isocentric
plane that is orthogonal to the beam.
where
MSF = the Wedge/Compensator Scatter Factor which you must set
R = the line connecting the beam source to the point r.
mod = the beam modifier
Len (R, mod) = the length of the line R through the beam modifier
MSC = the modifier scatter capacity. The modifier scatter capacity is a
function of the modifiers ability to interact with the beam and the
modifiers ability to scatter photons into the phantom. For
compensators this function has a value very close to zero.
mod
Typical values for the wedge scatter factor are: 0.5 for Varian machines and
0.2 for Elekta machines with an internal wedge.
SCD
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SAD - SCD
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Increasing the effective source size makes the shoulders and base of the X
and Y profiles rounder. Decreasing the effective source size makes the
shoulders and base of the X and Y profiles more square.
Transmission Factors
The XY Jaw Transmission Equal option allows you to select if your
machine has single or multiple jaw transmission factors. The setting is
global for the machine, even though you select it for one of the models
and can change the transmission factors per model. If you select Yes, you
can enter one jaw transmission factor for both pairs of jaws. If you select
No, you can enter one transmission factor for the top/bottom pair and
another for the right/left pair. If you set MLC Replaces Jaws to Yes in the
MLC Editor, you can only set a single jaw transmission factor.
The jaw transmission factor (0.001-1.00) specifies the fraction of the
energy fluence transmitted through the jaws. This models the actual jaw
transmission.
The MLC transmission factor (0.001-0.200) specifies the fraction of the
energy fluence transmitted through the MLC leaves.
N OT E The MLC transmission field only appears if the machine has an MLC. The MLC
transmission factor cannot be edited during planning.
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3.5.1 E_TuneAllInSections
This sequence currently produces the best results for tuning an entire
model. The sequence tunes the electron contamination parameters in
conjunction with the spectrum while tuning the entire model. It also
separates the X and Y focal spot size tuning and optimizes the left/right
jaw transmission, top/bottom jaw transmission, MLC transmission, and
arbitrary fluence profiles. The left/right jaw transmission optimization
only uses X profiles, while the top/bottom jaw transmission only uses Y
profiles. The MLC transmission is optimized after the jaw transmissions,
and it only uses profiles that include the MLC.
N OT E The MLC parameters Rounded Leaf Tip Radius, Tongue and groove width and
Additional interleaf leakage transmission are not included in this automodeling
sequence, but their effects are included in the dose computation.
When jaw transmissions are optimized, only the profiles in the direction of the jaws
are used. When MLC transmissions are optimized, only the profiles in the direction
of the MLC are used.
3.5.2 FineTuneCrossBeam
Use this sequence to fine-tune the cross-beam shape parameters. You can
also use this sequence to fine-tune a model copied from the model library
to your machine.
This sequence does not tune the Off-Axis Softening parameter nor the Inc
Fluence Cone Angle and Radius for small fields. These parameters should
only be tuned using large fields. Because of the relationship between cross-
beam low dose and cross-beam high dose parameters, you should not
apply this sequence to a model that does not include large and small fields.
If a single model exists for all fields, this sequence does not use the wedged
fields for optimization. However, if the model is for wedged fields, the
software uses only the corresponding wedged fields for optimization.
3.5.3 FineTuneSpectrum
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Use this sequence to fine-tune the beam spectrum. You can use this
sequence to fine-tune a model copied from the model library to your
machine.
If a single model exists for all fields, this sequence does not use the wedged
fields for optimization. However, if the model is for wedged fields, the
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3.5.4 FineTuneECAndSpectrum
Use this sequence to fine-tune the beam spectrum in the presence of
electron contamination, which obtains a best fit in the buildup region of
the depth dose curves while maintaining agreement at deeper depths. The
success of this sequence depends on an accurate fit of the electron
contamination for the tuning of the spectrum.
If a single model exists for all fields, this sequence does not use the wedged
fields for optimization. However, if the model is for wedged fields, the
software uses only the corresponding wedged fields for optimization.
3.5.5 FineTuneECInParallel
Use this sequence to fine-tune the electron contamination. You should use
this sequence only after the beam spectrum has been tuned.
Most of the electron contamination parameters are tuned simultaneously
for all fields corresponding to the model being tuned. The Depth
parameter is not tuned. The Off Axis Coefficient is tuned as a separate
phase from the other parameters.
If a single model exists for all fields, this sequence does not use the wedged
fields for optimization. However, if the model is for wedged fields, the
software uses only the corresponding wedged fields for optimization.
3.5.6 FineTuneECInSections
Use this sequence to fine-tune the electron contamination after the beam
spectrum has been tuned. Most of the electron contamination parameters
are tuned in sections for all fields corresponding to the model being tuned.
The Depth parameter is not tuned. The Depth Fraction and the Scale
Fraction are tuned separately. The Off Axis Coefficient is tuned as a
separate phase from the other parameters.
If a single model exists for all fields, this sequence does not use the wedged
fields for optimization. However, if the model is for wedged fields, the
software uses only the corresponding wedged fields for optimization.
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3.5.7 FineTuneECSequentially
Use this sequence to fine-tune the electron contamination. You should use
this sequence only after the beam spectrum has been tuned. The electron
contamination parameters are tuned sequentially. The optimization starts
with medium size fields and then progresses to all fields. This results in
electron contamination parameters that are biased toward the medium size
fields. The Depth parameter is not tuned. The Off Axis Coefficient is
tuned as a separate phase from the other parameters.
If a single model exists for all fields, this sequence does not use the wedged
fields for optimization. However, if the model is for wedged fields, the
software uses only the corresponding wedged fields for optimization.
3.5.8 FineTuneModelForOpenAndWedgedFields
Use this sequence to fine-tune all aspects of the model both for open fields
and wedged fields. The assumption is that you have a single model for all
fields (wedged and open), and that you have performed open field tuning.
3.5.9 FineTuneModifierScatter
Use this sequence to fine-tune all aspects of the model for the wedged
fields to which it corresponds. The assumption is that you have copied this
model from the model library or from the open field model, and that you
need to fine-tune it to fit the wedged fields.
3.5.10 FineTuneAllForWedge
Use this sequence to fine-tune all aspects of the model for the wedged
fields to which it corresponds, including left/right jaw transmission,
top/bottom jaw transmission, MLC transmission, and arbitrary fluence.
The assumption is that you have copied this model from the model library
or from the open field model, and that you need to fine-tune it to fit the
wedged fields.
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N OT E The MLC parameters Rounded Leaf Tip Radius and Tongue and groove width are
not included in this automodeling sequence, but their effects are included in the
dose computation.
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3.5.11 FineTuneModelForFieldSize
Use this sequence to fine-tune a model for the currently selected field size.
The assumption is that you have copied this model from the model
library, or preferably from the open field model, and that you need to fine-
tune it.
This sequence does not tune the cross-beam parameters, as these must be
tuned with consideration for large fields. This sequence also does not tune
the modifier scatter parameter.
WA R N I N G C1, C2, and C3 are used to produce a function of field size. They should be the same
for each model when the models have been created for each field size.
If you have photon models that are in the same wedge group but have different
field sizes, you cannot assign different values for C1, C2, and C3. It causes problems
in the interpolation over field size for the different field-size specific models and will
prevent commissioning of the machine.
for the 10 cm x 10 cm reference field (or for fixed jaw machines, the field
defined by the user). It computes dose to the calibration point and
compares the dose to the user-supplied calibrated output. Then the
software corrects the ratio of measured and computed data using the
incident energy fluence. This absolute calibration factor is used for every
field size when creating the incident energy fluence image.
The next step is to determine the field-size dependent correction factors.
(The OFcs are relative to the 10 cm x 10 cm reference, or for fixed jaw
machines, the field defined by the user.) First, the software computes OFp,
which is the ratio of the computed dose for the specified field over the
reference field using the convolution/superposition dose model with only
the 10 cm x 10 cm absolute calibration applied, or for fixed jaw machines,
the field defined by the user. With the measured OF and the computed
OFp, we can deduce that OFc = OF/OFp. This computation is made for
every measured relative output factor and is tabulated per field size and
plotted in the Photon Output Factor Computation window. In Planning
mode the OFc is interpolated via equivalent squares. For non-fixed jaw
machines, the equivalent square is computed using the jaw-defined field,
and for fixed jaw machines it is computed using the minimum
circumscribing rectangle surrounding the MLC-defined field.
The final incident energy fluence for each beam is therefore the product of
the fluence from the standard head model, the absolute calibration factor,
and the field-size dependent OFc.
CAUTION When modeling, you want to achieve uniformity of the OFc among the various field
sizes. You can adjust the Gaussian flattening filter scatter source to obtain this
uniformity. For more details on the Gaussian function, see the next section.
visible region of the source can be either the MLC or the jawwhichever
device produces the smallest visible region.
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flattening filter
scatter source distribution
flattening filter
head scatter
N OT E The primary fluence plus the head scatter representation (the Gaussian integral) is
the final incident fluence. The Gaussian flattening filter scatter source distribution
is defined at the source-to-flattening-filter distance. The cone radius is defined at
the isocenter plane.
The output factors (OFc) computed in the current version of the software
represent the head scatter that is not already included in the photon
model. If all head scatter effects have been incorporated into the model,
OFc should be 1.00 for all field sizes. In practice, there may be a slight
increase in computed OFc values with increasing field size, although it is
not unreasonable to see small decreases if the Gaussian scatter source
slightly overestimates the amount of scatter generated by the flattening
filter.
Because the softwares computed OFc values reflect only the head scatter
effects not included in the new model, they differ from the traditional
Collimator Scatter Factors (Sc).
OF c = ( OF ) ( OF p )
D ( i ) OF c = 1
OF p ( i ) = -------------------------
D ( ref )
D OFc ( i ) ( i ) = D OF c = 1 ( i ) OF c ( i )
DOFc(i)(i) is the final dose calculation when the proper OFc is used for the
given field size, and is synonymous with D(i).
Using the previous equations in this section, and realizing that by
definition
OF c ( ref ) = OF p ( ref ) = 1
WA R N I N G The accuracy of the treatment planning dose calculation depends on the quality of
the data entered in the physics tool. If the quality of this data is poor, or if the
computed dose is not verified with measured data, the dose calculation may be
inaccurate.
= SAD
(e.g., 100 cm)
Water
surface
Central axis
depth dose
As defined by Khan, the practical range is the depth of the point where
the tangent to the descending linear portion of the curve (at the point of
inflection) intersects the extrapolated background, as shown in the
illustration below.
Relative Depth Dose
Depth (cm) Rp
Square Field Sizes 2, 3, 4, 5, 6, 8, 10, 15, 20, 25, or open cone field size (in cm)
= SAD
(e.g., 100 cm)
Water
surface
Central axis
depth dose
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Source to chamber Equally spaced distances beyond the nominal SSD (i.e., for a
distances 100 cm SAD machine, measure at 100 cm, 105 cm, 110 cm,
115 cm, and 120 cm source to probe distances)
Resolution 1 mm spacing
Measurement Limits Measurements should extend as far outside the field boundary
as possible
To determine the position of the virtual SSD, plot the beam width at the
50% dose positions (FWHM) versus the source to chamber distance for
the in-air cross-axis profiles. Project the best fit line to the width of zero
(FWHM = 0) and record the source to chamber distance. Then subtract
the source to chamber distance from the calibration setup SSD to obtain
the virtual SSD. For example, for the plot shown below, the virtual SSD
would be approximately 90.1 cm. You must calculate the virtual SSD for
each electron energy that you commission.
25
20
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FWHM (cm)
15
10
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0
0 25 50 75 100 125
Determining Sigma-Theta-X
This parameter characterizes the angular scattering of electrons in air.
Sigma-theta-x can be calculated from the 80% - 20% penumbra width as
described by Hogstrom (1981, 1987). Plot the 80% - 20% penumbra
width in air versus the isocenter to chamber distance (ICD) for a large
field.
2.0
0.0
-10 -5 0 5 10 15 20
Determine the slope of this plot and use it in the following equation to
calculate sigma-theta-x.
x = 0.595 slope
80% - 20%
1.75 0.5
------------------------ = 0.0625
20 0
so
x = 0.0372
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Field/Cone Sizes 2 cm, 3 cm, 4 cm, 6 cm, 8 cm, 10 cm, 15 cm, 20 cm, and 25 cm
and your maximum field size.
Measurement Limits Measurements should extend as far outside the field boundary
as possible.
N OT E You do not need to measure these field sizes in each cone. You only need to
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measure them in a clinically relevant cone, for example 2 cm, 3 cm, 4 cm, and 6 cm
in a 6 cm x 6 cm cone, 8 cm and 10 cm in a 10 cm x 10 cm cone, and then the open
15 cm, 20 cm, and 25 cm cones.
= SAD
Water
surface
x
y
100 cm
105 cm
2 cm 110 cm
115 cm
120 cm
6 cm
100 cm
105 cm
3 cm 110 cm
115 cm
120 cm
All output factors are relative to the open 10 cm x 10 cm field at 100 SSD
and are measured at dmax. Monitor units will not be available outside of the
range of measurements. See the Electron Physics & Physics Utilities
chapter of the Pinnacle3 Physics Instructions for Use for more information.
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5 Compute the profiles again to verify that the changes to the off-axis ratios
improved the fit between the measured and computed profiles.
If the profiles still do not match well, repeat step 2. For each point that
needs to be changed, multiply the new off-axis ratio by the previous one
and enter the value in the off-axis ratio table. Continue to make
adjustments until you obtain a good fit between the measured and
computed profiles.
6 After adjusting all the other parameters, you can tune the FMCS
parameter. Watch the penumbra region of cross-beam profiles at depths
greater than R90 for the goodness of fit between the measured and
computed profiles. Typically the FMCS ranges from 1.2 to 1.4. If you
need to exceed 1.4 to obtain a good fit, something else is wrong with the
model.
7 When you finish, return to the Electron Physics Tool window and click
the Save All Machines button to save the computed dose lookup tables.
CAUTION When tuning the off-axis ratios, do not extend your corrections into the high dose
gradient region. Doing so within this region could cause dose artifacts for the
interpolated field sizes.
To determine how to adjust the off-axis ratios (OAR), first compute the
profile at R90/2 with off-axis ratios of 1.0 at x = -30, 0, and 30. X defines
the off-axis distance. Then, in regions of the profile where the measured
and computed profiles do not match well, calculate the off-axis ratios for a
number of points using the following equation.
Measured ( x )
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OAR ( x ) = -------------------------------
-
Computed ( x )
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The following example shows the measured and computed profile for a
10 cm cone.
In this profile, the regions from -5.0 to -3.0 and from 3.0 to 5.0 have the
most error between the measured and computed profiles. By determining
the ratios of the measured values to the computed values at a number of
points in these regions and entering the ratios in the Off-Axis Ratio table,
you can reshape the computed profile to correct the errors. Enter points at
the edges of these regions in the table with Off-Axis Ratios of 1.0.
To correct the profile in the previous example, the following Off-Axis
Ratio was entered.
OF cal
A cal = ------------------------------------------------------------------------------
-
D pb ( 10 10, 10 10, 100, d max )
where
OFcal = the measured output factor for the calibration condition, and
Dpb(cone size, cutout size, SSD, depth) = the value computed by the
pencil beam algorithm in a flat water phantom along the central axis of
the beam.
Next tabulate the correction factors for a range of square field sizes and
SSD. These correction factors (OFc) relate the pencil beam dose computed
for square fields back to the calibration condition:
where
OFrel = the measured output factor relative to the calibration condition
for the particular square field of interest (W).
Then for any square field (W), cone, and SSD, by applying the correction
factors you can compute the actual dose per monitor unit within the dose
volume obtained by the pencil beam algorithm.
D
----------------- = OF c A cal D pb ( r )
MU ( r )
If the pencil beam computation were perfect, the OFc value would be
constant over all SSD and field sizes. We know that the accelerator output
changes with jaw settings, and each electron cone uses different jaw
settings; therefore, we can reasonably expect the OFc to be dependent on
the electron cone selection.
In the planning tool, the pencil beam algorithm is scaled by the OFc to
obtain the dose per monitor unit in the beams dose grid.
The OFc is tabulated for each cone at discrete SSDs, and linearly
interpolated over SSD to determine the appropriate value for any
intermediate SSD. Linear interpolation is used because the inverse square
effects are incorporated into the pencil beam algorithm and are accounted
for in the OFp value.
The OFc is also tabulated for a discrete set of square field sizes. The OFc
value for rectangular fields is found by combining the OFc values for the
square fields matching the size of the rectangular field edges through the
square root relationship described in Khan and TG25 (6,7).
OF c ( X, Y ) = OF c ( X, X ) OF c ( Y, Y )
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Minimum area
circumscribing
rectangle
Field shape
WA R N I N G The accuracy of the treatment planning dose calculation depends on the quality of
the data entered in the physics tool. If the quality of this data is poor, or if the
computed dose is not verified with measured data, the dose calculation may be
inaccurate.
D D penc ( SSD, d, r, W c )
---------- ( SSD, d, r, W c ) = --------------------------------------------------------------------
- TAR ( d iso, W c ) d I ( W c )
MU D penc ( SSD, d iso, ( r = 0 ), W c )
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where:
Dpenc(SSD, d, r, Wc) is the stored pencil beam dose distribution in water
at SSD, depth d and position r for a collimator of size Wc as measured at
the isocenter,
Dpenc (SSD, diso, r = 0, Wc) is the stored pencil beam dose distribution in
water at SSD, at isocenter on the central axis for a collimator of size Wc
as measured at the isocenter, where the isocenter is at depth diso from the
patient surface,
TAR(diso, Wc) is the tissue-air-ratio at the isocenter,
dI (Wc) is the dose per monitor unit to a small mass of tissue in air at the
isocenter.
Dpenc(SSD, d, r, Wc) is the product of the fractional depth dose
FDD(SSD, d, Wc) and the off-axis factor OAF(SSD, d, r, Wc).
The above equation can then be expressed in terms of more standard
dosimetric quantities:
where:
FDD(SSD, d, Wc) is the fractional depth dose at SSD and depth d for a
collimator of size Wc as measured at the isocenter:
D (SSD,d, r = 0, W c)
FDD (SSD,d, W c) = -----------------------------------------------------
-
D (SSD,d max, r = 0, W c)
OAF(SSD, d, r, Wc) is the off-axis factor and is the dose profile of a beam
with a given SSD at a given depth normalized to the value at the central
axis:
D (SSD,d, r, W c)
OAF (SSD,d, r, W c) = ----------------------------------------------
D (SSD,d, r = 0, W c)
D ( d iso, W c )
TAR ( d iso, W c ) = --------------------------
-
D air ( W c )
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SDD + d iso 2
TAR (d iso,W c) = FDD (SSD,d iso, W c) BSF ( W c ) ----------------------------
-
SDD + d max
where dmax is the depth of maximum dose along the central axis.
BSF ( 10 10 ) D air
d I ( W c ) = OF ( W c ) --------------------------------- ---------
- ( 10 10 )
BSF ( W c ) MU
WA R N I N G In order to correctly generate the tabular dose data, the depth dose and cross-axis
measured data profiles must contain one and only one dose value for each position
coordinate. In addition, all depth/distance coordinates in the profiles must increase
or decrease monotonically.
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For every collimator used with a given beam energy, you must measure
two depth dose curves: one with an SSD of 80 cm and one with an SSD of
100 cm. These depth dose curves will be used to generate the stereotactic
radiosurgery dose lookup tables. Additional measurement geometries may
be measured, imported into the Stereotactic Radiosurgery Physics tool and
compared to the computed profiles for quality assurance purposes.
However, only profiles measured at 80 cm SSD and 100 cm SSD will be
used to generate the dose lookup tables.
WA R N I N G The depth dose data is assumed to have a depth value that is a positive measure of
distance from the surface of the water. For example, a measurement taken at one
centimeter below the surface of the water is assumed to have a depth of 1.0 and not
-1.0. Do not enter depth dose data with negative depth coordinates or you will get
erroneous results.
Measurement Limits 0 to 30 cm
depth dose
resolution
with 0.20 cm
resolution
Reading at d max ( W c )
ROF = ----------------------------------------------------------
-
Reading at d max ( 10 10 )
The term backscatter factor is the tissue-air ratio at the depth of maximum
dose on the central axis of the beam. It is defined as the ratio of the dose
on the central axis at the depth of maximum dose to the dose at the same
point in free space (Khan, 1994).
Because
TAR ( d, W c )
(2) TMR ( d, W c ) = ----------------------------
-
BSF ( W c )
TMR ( d, W c ) = TAR ( d, W c )
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(3)
D air BSF ( 10 10 )
(4) d I ( W c ) = OF ( W c ) ---------
- ( 10 10 ) ---------------------------------
MU BSF ( W c )
D air
(5) d I ( W c ) = OF ( W c ) ---------
- ( 10 10 ) BSF ( 10 10 )
MU
The backscatter factor is the dose at dmax divided by the dose in free space
at the same point. Thus, the second two terms of this equation can be
multiplied, and the air measurement cancels, yielding the following
equation:
D
(6) d I ( W c ) = OF ( W c ) ---------- ( d max, 10 10 )
MU
D D penc (SSD, d, r, Wc )
(7) --------- (SSD, d, r, Wc ) = -------------------------------------------------------
- TAR (d iso,Wc ) d I (Wc )
MU D penc (SSD, d iso, r = 0, Wc )
where:
Dpenc(SSD, d, r, Wc) is the dose at depth d, and off axis distance r from
the stored pencil beam dose distribution in water at SSD, for a
collimator of size Wc,
Dpenc (SSD, diso, r = 0, Wc) is the dose at isocenter for a collimator of size
Wc at SSD, where the isocenter is at depth diso from the patient surface,
TAR(diso, Wc) is the tissue-air-ratio at the isocenter,
dI (Wc) is the dose per monitor unit to a small mass of tissue in air at the
isocenter.
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Replacing TAR with TMR and replacing dI with the reduced dI defined in
equation 6 above yields the familiar TMR equation:
D D penc (SSD, d, r, Wc )
(8) --------- (SSD, d, r,Wc ) = -------------------------------------------------------
- TMR (d iso,Wc ) d I (Wc )
MU D penc (SSD, d iso, r = 0, Wc )
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(10) d I ( W c ) = OF ( W c )
This chapter describes the Pinnacle3 brachytherapy dose algorithm and the
required source characteristic data.
CAUTION No heterogeneity corrections are applied, regardless of whether you plan from CT
or film.
P
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.
.
. ds = distance through source
df = distance through wall (filter)
dl = distance through water
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Each element is treated as a point source when the dose rate for a line
source is computed. The source is divided into a minimum of 20 voxels in
each dimension. Sources that are larger than 0.5 cm use voxels of
0.025 cm in size.
The absorbed dose rate at a time t to point p from a single shielded line
source, Dp (t), can be determined from the following equation.
N
1 ( d d )
D p ( t ) = f med A ( t ) ---- e s s f f ( ( T ( d l ) ) d i )
2
N
i
where:
fmed is the exposure-to-dose conversion factor for soft tissue.
G is the specific exposure rate constant (R cm2 mCi-1 h-1) for the source.
A(t) is the activity, in mCi, of the source at the time of treatment. If
activity is specified in units other than mCi, the system internally
converts the activity to mCi for the dose calculation.
N is the number of point sources (elements) used to model the source.
s is the linear absorption coefficient of the source material.
ds is the path length of the radiation through the source.
f is the linear absorption coefficient of the wall material.
df is the path length of the radiation through the wall.
dl is the path length of the radiation through water.
di is the distance from the ith point source to the dose point P.
di = ds + df + dl
T(dl), the tissue correction, is the polynomial (i.e., Meisberger
coefficients):
Exposure in water 2 3
T ( d l ) = --------------------------------------- = A + Br + Cr + Dr
Exposure in air
A lookup table is computed which stores the shape of the dose. This
table is calculated using the summation:
N
1 ( d d )
---- e s s f f ( ( T ( d l )) d i 2 )
N
i
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CAUTION The dose algorithm used by the Pinnacle3 software requires the entry of a tissue
correction factor, T(dl), represented by Meisberger polynomial coefficients. This
factor is different from the radial dose function, g(r), described by the TG43 dose
formalism (Nath, et al.).
CAUTION Because labeling in the Pinnacle3 software once referred to Radial Dose Function
data entry, it was possible to conclude that the radial dose function coefficients
published for the TG43 dose formalism could be used. The values for the radial dose
function coefficients provided for the TG43 formalism should be used only with a
TG43 dose algorithm. If they are used with any other dose formalism, such as the
Quantization Method implemented in the Pinnacle3 software, significant dose
calculation errors may result (Cassell, A fundamental approach to the design of a
dose-rate calculation program for use in brachytherapy, British Journal of
Radiology, 1983).
If the source is a point source rather than a line source, the distance
through the source (ds) and the distance through the wall (df ) are both 0,
and exp(0) = 1. Additionally, since there is only one point source, activity
summation is not necessary.
P
Source
becomes
2
D p ( t ) = f med A ( t ) ( ( T ( d l ) ) d )
A ( t ) = A ( t cal ) e ( t tcal )
where
tcal is the time of calibration
t is the time of treatment and
= ln(2) / half life
Activity conversions
In all internal calculations, the system defines activity (A (t)) in mCi.
When the activity is defined in units other than mCi, it is converted to
mCi using the following methods.
mCi 1.0
R*cm2/h 1.0 /
U 1.0 / ((W/e) * )
where:
is the exposure rate constant in units of R cm2 mCi-1 hr-1, and
W/e is the air exposure to dose constant expressed in cGy/R
D ( r , ) = S k [ G ( r, ) G ( r 0 , 0 ) ]g ( r )F ( r, )
where:
Sk is the air kerma strength of the source (units of U)
is the dose rate constant (units of cGy h-1 U-1)
G(r,)/G(r0,0) is the geometry factor normalized to the reference point
g(r) is the radial dose function
F(r, ) is the anisotropy function.
Each of these quantities or functions and the reference point (r0, 0) are
described in the following sections.
The reference point (r0, 0) lies on the transverse bisector of the source at a
distance of 1 cm from its center (r0 = 1 cm and 0 = /2).
P(r,)
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r
P(r0,0) x
r0 = 1 cm
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1 2
z
L
t
S k = K ( d )d
2
The calibration distance must be large enough that the source may be
treated as a mathematical point. In actual practice, air kerma rate
standardization measurements are performed in air and corrections for air
attenuation are applied if needed. While the measurements for source
strength calibration may be performed at any large distance, d, it is
customary to specify the air kerma strength in terms of a reference
calibration distance, d0, which is usually 1 m. The physicist typically does
not perform the in-air calibration; a standardization laboratory does.
However, the physicist should verify the accuracy of source strength
provided by the vendor. Typically, you should have a well-type ionization
chamber with a calibration traceable to the national standards for each
type of brachytherapy source.
If kerma, time, and distance are assigned units of Gy, h, and m,
respectively, Sk will have units of Gy m2 h-1, as recommended by the
TG43 report. This unit is denoted by the symbol U:
1 U = 1 unit of air kerma strength = 1 Gy m2 h-1 = 1 cGy cm2 h-1
The geometric relationship between the point of output determination
and an arbitrary filtered source have been described previously by
Williamson and Nath.
The dose rate constant is the dose rate to water at 1 cm on the transverse
axis of a unit air kerma strength source in a water phantom. The dose rate
constant is an absolute quantity, unlike the normalized (relative) quantities
that follow in this section. Liquid water is the reference medium used to
specify the dose rate constant as well as relative dose distribution
parameters. The 1 cm distance is specified along the transverse axis of the
actual source (rather than an idealized point source) relative to its
geometric center. Mathematically, the dose rate constant is
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= D ( r 0 , 0 ) S k
The geometry factor accounts for the variation of relative dose due only to
the spatial distribution of activity within the source, ignoring photon
absorption and scattering in the source structure. It is defined as
--------------------------------------------------
v [ ( r' ) dV' r' r ]
2
G ( r, ) = -
v ( r' ) d V'
where L is the active length of the source and is the angle subtended by
the active source with respect to the point (r, ) [ = 2 - 1].
Pinnacle3 reports G(r,)/G(r0,0) when it computes the Geometry
function, which normalizes the displayed table to the reference point
(r0,0).
CAUTION If you manually enter TG43 geometry factors, Pinnacle3 will automatically
normalize them to be 1 at a distance of 1 cm from the center of the source. This
function is indicated by the following equation, which appears when you manually
enter TG43 geometry factors: G(r, theta)/G(1 cm, 90 deg).
The radial dose function, g(r), accounts for the fall-off of dose rate along
the transverse axis due to absorption and scattering in the medium. It is
defined as
g ( r ) = D ( r, 0 )G ( r 0, 0 ) D ( r 0, 0 )G ( r, 0 )
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The radial dose function applies only to transverse axis (only for points
with an angle of 0, which is equal to /2). It can be influenced by
filtration of photons by the encapsulation and source materials.
The function g(r) is similar to a normalized transverse-axis tissue-
attenuation factor or an absorbed dose to kerma in free space ratio. The
above definition of radial dose function is different from the older (Dale)
definition.
This function accounts for the anisotropy of dose distribution around the
source, including the effects of absorption and scatter in the medium. It is
defined as
F ( r, ) = D ( r, )G ( r, 0 ) D ( r, 0 ) G ( r, )
D ( r ) = ------ D ( r, ) d
1
0
4
4
If we substitute the general TG43 equation below into the one above:
D ( r, ) = S k [ G ( r, ) G ( r 0, 0 ) ]g ( r )F ( r, )
The factor an (r) is the ratio of the dose rate at distance r (averaged with
respect to solid angle) to dose rate on the transverse axis at the same
distance. For the sources, (r) is less than 1, having values ranging from
0.91 to 0.97 depending upon the source. For distances greater than the
source active length, the equation for dose around a source using point-
source approximation simplifies to:
D ( r ) = S k r 0 r g ( r ) an ( r )
2 2
Anisotropy constant, an
The anisotropy factor (r) may be approximated by a distance-
independent constant, an, which we call the anisotropy constant. It is
usually less than 1.00. Thus, the anisotropy factor, an(r), in the above
equation can be replaced by a constant an without a significant loss in
accuracy. Point source approximation, as shown in the two previous
equations, gives a dose rate at the reference point in the medium on the
transverse bisector at 1 cm from the source, equal to an(r) for a unit air
kerma strength source. Thus, dose rate on the transverse axis in the
medium is somewhat lower using the point-source approximation than
4535 604 45211 A
This chapter explains the following aspects of file handling with Pinnacle3:
The first section lists manufacturers whose water phantom data is
compatible with Pinnacle3.
The next section explains how to import measured data files into
Pinnacle3 using the full or simple ASCII format for dose profiles.
The last section explains how to copy DOS-formatted files to the
system hard drive.
-y
-x +x
Left Right
+y
Bottom
. .
Depth or Offset Measured Dose
Profile Type Measurement Parameter A Measurement Parameter B
Number of Points
Philips Medical Systems
34.000000 28.900000
34.250000 28.700001
34.500000 28.500000
34.750000 28.299999
Philips Medical Systems
35.000000 27.799999
The worksheets in this section provide checklists for the physics data
required by the Pinnacle3 treatment planning system.
The machine description worksheets list the physical description
information required for the machines. These worksheets duplicate
portions of the physics tool windows into which the data must be entered.
Details on the machine physical description information can be found in
the Physical Machine Characteristics chapter of this manual.
The measured data worksheets summarize the measured data required for
each treatment modality. These worksheets can be used as checklists when
measuring machine data to make sure that you measure all of the data
required for each modality. Detailed descriptions of the measured data
requirements can be found in the chapters of this manual that cover each
modality. The worksheets list the data which must be collected for each
measurement geometry for each energy on every machine.
Make as many copies of the worksheets as necessary.
4535 604 45211 A
Philips Medical Systems
Physicist: Date:
Machine name:
Jaw name
Can be asymmetric?
Minimum position
Maximum position
Default position
Decimal places
Top
Table
-y
-x +x
Left Right
+y
Bottom
Physicist: Date:
Machine name:
Setting Value
Minimum angle
Maximum angle
Default angle
Decimal places
Setting Value
Minimum angle
Maximum angle
Default angle
Decimal places
*Some machines have a tray opening that never faces the gantry. Enter the angle as if you were
able to rotate the tray opening to face the gantry.
Philips Medical Systems
Physicist: Date:
Machine name:
Setting Value
Minimum angle
Maximum angle
Default angle
Decimal places
Arc allowed?
CW or CCW
CW only
CCW only
Physicist: Date:
Machine name:
Delivery parameters
Setting Value
Physicist: Date:
Machine name:
Setting Value
Maximum MU setting
When MU exceeded:
Physicist: Date:
Machine name:
Setting Value
Vendor
Bank names
For the MLC leaf positions, is the Top (X2) jaw +Y or -Y?
4535 604 45211 A
For the MLC leaf positions, is the Left (Y2) jaw +X or -X?
Setting Value
Setting Value
4535 604 45211 A
Physicist: Date:
Machine name:
Wedge information
You only need to provide values for the type of wedge you are using
(physical or dynamic). You can make copies of this page, if necessary, if
you will be using multiple wedges.
Wedge angle
Wedge Material
Density (gm/cm3)
Length (cm)
Calibration constant
Transmission factor
The Left, Right, Top and Bottom jaw labels in the above table refer to the
jaws indicated in the following illustration.
Top
Table
-y
-x +x
Left Right
+y
Bottom
Physicist: Date:
Machine name:
Wedge name:
When the wedge profile values are entered in the software, the values for
the thick end of the wedge must be entered first. To define the thickness of
the heel of the wedge, the first offset value should be entered twice: once
with a thickness of 0.0 and again with the measured thickness. The
thickness does not include any base on which the wedge is mounted.
Physicist: Date:
Machine name:
Setting Value
Physicist: Date:
Machine name:
Electron cones
Setting Value
Manufacturer code
Width
Length
Setting Value
Manufacturer code
Width
Length
Setting Value
Manufacturer code
Width
Length
Philips Medical Systems
Setting Value
Manufacturer code
Width
Length
Physicist: Date:
Machine name:
Physicist: Date:
Machine name:
Tolerance tables
Physicist: Date:
Machine name:
Setting Value
Enter the allowable dose rates for the machine in the table
cells at the right. The first value should be the maximum dose
rate for the energy, and subsequent values should be
monotonically decreasing.
4535 604 45211 A
Physicist: Date:
Machine name:
Energy:
Field size = 5 cm x 5 cm
SSD = 100
Recommended resolution for profiles: 0.20 cm
X Profile 5 cm
Y Profile 5 cm
X Profile 10 cm
Y Profile 10 cm
X Profile 20 cm
Y Profile 20 cm
X Profile dmax
Y Profile dmax
Physicist: Date:
Machine name:
Energy:
Field size = 10 cm x 10 cm
SSD = 100
Recommended resolution for profiles: 0.20 cm
X Profile 5 cm
Y Profile 5 cm
X Profile 10 cm
Y Profile 10 cm
X Profile 20 cm
Y Profile 20 cm
X Profile dmax
Y Profile dmax
Physicist: Date:
Machine name:
Energy:
Field size = 20 cm x 20 cm
SSD = 100
Recommended resolution for profiles: 0.20 cm
X Profile 5 cm
Y Profile 5 cm
X Profile 10 cm
Y Profile 10 cm
X Profile 20 cm
Y Profile 20 cm
X Profile dmax
Y Profile dmax
Physicist: Date:
Machine name:
Energy:
Field size = 20 cm x 5 cm
SSD = 100
Recommended resolution for profiles: 0.20 cm
X Profile 5 cm
Y Profile 5 cm
X Profile 10 cm
Y Profile 10 cm
X Profile 20 cm
Y Profile 20 cm
X Profile dmax
Y Profile dmax
Physicist: Date:
Machine name:
Energy:
Field size = 5 cm x 20 cm
SSD = 100
Recommended resolution for profiles: 0.20 cm
X Profile 5 cm
Y Profile 5 cm
X Profile 10 cm
Y Profile 10 cm
X Profile 20 cm
Y Profile 20 cm
X Profile dmax
Y Profile dmax
Physicist: Date:
Machine name:
Energy:
Field size = 30 cm x 30 cm
SSD = 100
Recommended resolution for profiles: 0.20 cm
X Profile 5 cm
Y Profile 5 cm
X Profile 10 cm
Y Profile 10 cm
X Profile 20 cm
Y Profile 20 cm
X Profile dmax
Y Profile dmax
Physicist: Date:
Machine name:
Energy:
X Profile 5 cm
Y Profile 5 cm
X Profile 10 cm
Y Profile 10 cm
X Profile 20 cm
Y Profile 20 cm
X Profile dmax
Y Profile dmax
Physicist: Date:
Machine name:
Energy:
Jaw size = 20 cm x 20 cm
MLC field size = 2 cm x 2 cm
SSD = 100
Recommended resolution for profiles: 0.20 cm
X Profile 5 cm
Y Profile 5 cm
X Profile 10 cm
Y Profile 10 cm
X Profile 20 cm
Y Profile 20 cm
X Profile dmax
Y Profile dmax
Physicist: Date:
Machine name:
Energy:
Jaw size = 20 cm x 20 cm
MLC field size = 3 cm x 3 cm
SSD = 100
Recommended resolution for profiles: 0.20 cm
X Profile 5 cm
Y Profile 5 cm
X Profile 10 cm
Y Profile 10 cm
X Profile 20 cm
Y Profile 20 cm
X Profile dmax
Y Profile dmax
Physicist: Date:
Machine name:
Energy:
Jaw size = 20 cm x 20 cm
MLC field size = 5 cm x 5cm
SSD = 100
Recommended resolution for profiles: 0.20 cm
X Profile 5 cm
Y Profile 5 cm
X Profile 10 cm
Y Profile 10 cm
X Profile 20 cm
Y Profile 20 cm
X Profile dmax
Y Profile dmax
Physicist: Date:
Machine name:
Energy:
Jaw size = 20 cm x 20 cm
MLC field size = 10 cm x 10 cm
SSD = 100
Recommended resolution for profiles: 0.20 cm
X Profile 5 cm
Y Profile 5 cm
X Profile 10 cm
Y Profile 10 cm
X Profile 20 cm
Y Profile 20 cm
X Profile dmax
Y Profile dmax
Physicist: Date:
Machine name:
Energy:
Jaw size = 20 cm x 20 cm
MLC field size = 15 cm x 15 cm
SSD = 100
Recommended resolution for profiles: 0.20 cm
X Profile 5 cm
Y Profile 5 cm
X Profile 10 cm
Y Profile 10 cm
X Profile 20 cm
Y Profile 20 cm
X Profile dmax
Y Profile dmax
Physicist: Date:
Machine name:
Energy:
Setting Value
Physicist: Date:
Machine name:
Energy:
The relative output factor for a wedged field is calculated using the
equation
Dose WFS
OF = -------------------
-
Dose CFS
4535 604 45211 A
where DoseWFS is the measured dose for the given wedged field size and
DoseCFS is the measured dose for the open calibration field. Note that the
ratio is not the wedge transmission factor because DoseCFS is the fixed open
calibration field dose.
Philips Medical Systems
WA R N I N G The wedge transmission factor cannot be substituted for the wedged field output
factors. Using the wedge transmission factor instead of wedged field output factors
will result in incorrect monitor unit calculations.
Physicist: Date:
Machine name:
Setting Value
Enter the allowable dose rates for the machine in the table
cells at the right. The first value should be the maximum dose
rate for the energy, and subsequent values should be
monotonically decreasing.
Physicist: Date:
Machine name:
X Profile 1 cm
X Profile 5 cm
X Profile 10 cm
X Profile 15 cm*
X Profile 20 cm
X Profile 25 cm
X Profile 30 cm
X Profile 1 cm
X Profile 5 cm
4535 604 45211 A
X Profile 10 cm
X Profile 15 cm*
X Profile 20 cm
X Profile 25 cm
Philips Medical Systems
X Profile 30 cm
* Profiles at these depths are not required but are recommended for increased accuracy.
Physicist: Date:
Machine name:
Energy:
Setting Value
Collimator-specific measurements
Reading at d max ( W c )
ROF ( W c ) = ----------------------------------------------------------
-
Reading at d max ( 10 10 )
Physicist: Date:
Machine name:
Setting Value
Enter the allowable dose rates for the machine in the table
cells at the right. The first value should be the maximum dose
rate for the energy, and subsequent values should be
monotonically decreasing.
4535 604 45211 A
Physicist: Date:
Machine name:
Energy:
Depth Dose Rp + 5 cm
Depth Dose Rp + 5 cm
Depth Dose Rp + 5 cm
Depth Dose Rp + 5 cm
Depth Dose Rp + 5 cm
Depth Dose Rp + 5 cm
Depth Dose Rp + 5 cm
Depth Dose Rp + 5 cm
Depth Dose Rp + 5 cm
Depth dose measurements in water must be made for each scanned square
field, otherwise the software cannot compute the profile.
Physicist: Date:
Machine name:
Energy:
SSD =
X Profile 1/2(R90)
Y Profile 1/2(R90)
X Profile R90
X Profile R70
X Profile R50
X Profile Rp + 2 cm
4535 604 45211 A
Philips Medical Systems
Physicist: Date:
Machine name:
Energy:
The following profiles must be measured in air. These profiles do not need
to be imported into Pinnacle3.
Cone Size =
Physicist: Date:
Machine name:
Energy:
Drift Distance: cm
This is the distance between the collimator and the surface of the phantom
for the standard setup SSD.
Cutout Material Photon Transmission Factor
Determine the photon dose transmitted through the cutout material. The
ratio of the blocked field dose to the open field dose is the cutout material
photon transmission factor.
Physicist: Date:
Machine name:
Energy:
Physicist: Date:
Machine name:
Energy:
N OT E The field sizes listed on this worksheet are the recommended sizes for a standard set
of electron output factors. If necessary, collect data for smaller field sizes to
accommodate smaller output factors in the individual cones.
Setting Value
6 9 12 15 18 20
3x3
4x4
6x6
10 x 10 3x3
4x4
6x6
8x8
10 x 10
15 x 15 3x3
4x4
6x6
8x8
10 x 10
12 x 12
15 x 15
20 x 20 4x4
6x6
8x8
10 x 10
12 x 12
15 x 15
18 x 18
20 x 20
25 x 25 4x4
6x6
Philips Medical Systems
8x8
10 x 10
12 x 12
15 x 15
18 x 18
20 x 20
25 x 25
6 9 12 15 18 20
3x3
4x4
6x6
10 x 10 3x3
4x4
6x6
8x8
10 x 10
15 x 15 3x3
4x4
6x6
8x8
10 x 10
12 x 12
15 x 15
20 x 20 4x4
6x6
8x8
10 x 10
12 x 12
15 x 15
18 x 18
20 x 20
4535 604 45211 A
25 x 25 4x4
6x6
8x8
10 x 10
Philips Medical Systems
12 x 12
15 x 15
18 x 18
20 x 20
25 x 25
6 9 12 15 18 20
3x3
4x4
6x6
10 x 10 3x3
4x4
6x6
8x8
10 x 10
15 x 15 3x3
4x4
6x6
8x8
10 x 10
12 x 12
15 x 15
20 x 20 4x4
6x6
8x8
10 x 10
12 x 12
15 x 15
18 x 18
20 x 20
25 x 25 4x4
6x6
Philips Medical Systems
8x8
10 x 10
12 x 12
15 x 15
18 x 18
20 x 20
25 x 25
6 9 12 15 18 20
3x3
4x4
6x6
10 x 10 3x3
4x4
6x6
8x8
10 x 10
15 x 15 3x3
4x4
6x6
8x8
10 x 10
12 x 12
15 x 15
20 x 20 4x4
6x6
8x8
10 x 10
12 x 12
15 x 15
18 x 18
20 x 20
4535 604 45211 A
25 x 25 4x4
6x6
8x8
10 x 10
Philips Medical Systems
12 x 12
15 x 15
18 x 18
20 x 20
25 x 25
6 9 12 15 18 20
3x3
4x4
6x6
10 x 10 3x3
4x4
6x6
8x8
10 x 10
15 x 15 3x3
4x4
6x6
8x8
10 x 10
12 x 12
15 x 15
20 x 20 4x4
6x6
8x8
10 x 10
12 x 12
15 x 15
18 x 18
20 x 20
25 x 25 4x4
6x6
Philips Medical Systems
8x8
10 x 10
12 x 12
15 x 15
18 x 18
20 x 20
25 x 25