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The Extracellular Domain of Neurotrophin Receptor p75 as a Candidate Biomarker for Amyotrophic Lateral Sclerosis

Figure 5

There are significant amounts of p75NTRECD in the urine of rapidly progressing compared to slowly progressing ALS patients.

Scatter plots show urinary p75NTRECD concentrations in ‘slowly progressive ALS’ (n = 7) and ‘rapidly progressive ALS’ (n = 7). The horizontal lines represent the mean, with 95% confidence interval. Progression rate is decline in ALSFRS-r per month. *Mann–Whitney test (p = 0.004).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0087398.g005