FOXO3
Внешний вид
FOXO3 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[26][27]
Искәрмәләр
[үзгәртү | вики-текстны үзгәртү]- ↑ 1,0 1,1 UniProt
- ↑ Essers M. Functional interaction between beta-catenin and FOXO in oxidative stress signaling // Science / H. Thorp — Northern America: AAAS, 2005. — 4 p. — ISSN 0036-8075; 1095-9203 — doi:10.1126/SCIENCE.1109083 — PMID:15905404
- ↑ 3,00 3,01 3,02 3,03 3,04 3,05 3,06 3,07 3,08 3,09 3,10 3,11 3,12 3,13 3,14 3,15 3,16 3,17 3,18 3,19 3,20 3,21 3,22 3,23 3,24 3,25 3,26 3,27 3,28 3,29 3,30 3,31 3,32 3,33 3,34 3,35 3,36 3,37 3,38 3,39 3,40 3,41 3,42 3,43 3,44 3,45 3,46 3,47 3,48 3,49 3,50 3,51 3,52 3,53 3,54 3,55 3,56 3,57 3,58 3,59 3,60 3,61 3,62 3,63 3,64 3,65 3,66 3,67 3,68 3,69 3,70 3,71 3,72 3,73 3,74 3,75 GOA
- ↑ 4,0 4,1 4,2 4,3 Ryall J. G., Peserico A., Chiacchiera F. et al. A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels // Cell Mol Life Sci — Birkhäuser, Springer Science+Business Media, 2013. — ISSN 1420-9071; 1420-682X — doi:10.1007/S00018-012-1244-6 — PMID:23283301
- ↑ 5,0 5,1 5,2 5,3 5,4 5,5 5,6 Tezil T., Fasano C., Peserico A. et al. Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy // Cell Death Dis. — London: Nature Publishing Group, 2018. — ISSN 2041-4889 — doi:10.1038/S41419-018-0336-0 — PMID:29445193
- ↑ Goruppi S. Deficiency of the transcriptional regulator p8 results in increased autophagy and apoptosis, and causes impaired heart function, Deficiency of the Transcriptional Regulator p8 Results in Increased Autophagy and Apoptosis, and Causes Impaired Heart Function // Mol. Biol. Cell, — American Society for Cell Biology, 2010. — ISSN 1059-1524; 1939-4586; 1044-2030 — doi:10.1091/MBC.E09-09-0818 — PMID:20181828
- ↑ Yang Y., Villén J., Esther B.E. Becker et al. A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span // Cell — Cell Press, Elsevier, 2006. — ISSN 0092-8674; 1097-4172 — doi:10.1016/J.CELL.2006.03.046 — PMID:16751106
- ↑ Katayama R. Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels // Cancer Res. / G. C. Prendergast — American Association for Cancer Research, 2008. — ISSN 0008-5472; 1538-7445 — doi:10.1158/0008-5472.CAN-08-0634 — PMID:18593906
- ↑ 9,0 9,1 9,2 Rosenwald A., Gaestel M., Cannell I. G. et al. The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis // Mol. Cell — Cell Press, Elsevier, 2011. — ISSN 1097-2765; 1097-4164 — doi:10.1016/J.MOLCEL.2011.01.023 — PMID:21329882
- ↑ 10,00 10,01 10,02 10,03 10,04 10,05 10,06 10,07 10,08 10,09 10,10 10,11 10,12 10,13 GOA
- ↑ 11,0 11,1 Löwenberg B. FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1 // J. Cell Biol. / J. Nunnari — Rockefeller University Press, 2004. — ISSN 0021-9525; 1540-8140 — doi:10.1083/JCB.200307056 — PMID:14734530
- ↑ 12,0 12,1 A Brunet, A Bonni, Zigmond M. J. et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor // Cell — Cell Press, Elsevier, 1999. — ISSN 0092-8674; 1097-4172 — doi:10.1016/S0092-8674(00)80595-4 — PMID:10102273
- ↑ 13,0 13,1 13,2 Wang K., Li P. Foxo3a regulates apoptosis by negatively targeting miR-21 // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2010. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M109.093005 — PMID:20371612
- ↑ Vaquerizas J. M., Teichmann S., Kummerfeld S. K. A census of human transcription factors: function, expression and evolution // Nature reviews. Genetics — United Kingdom: NPG, 2009. — ISSN 1471-0056; 1471-0064 — doi:10.1038/NRG2538 — PMID:19274049
- ↑ Vaquerizas J. M., Teichmann S., Kummerfeld S. K. A census of human transcription factors: function, expression and evolution // Nature reviews. Genetics — United Kingdom: NPG, 2009. — ISSN 1471-0056; 1471-0064 — doi:10.1038/NRG2538 — PMID:19274049
- ↑ 16,0 16,1 16,2 16,3 16,4 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
- ↑ 17,0 17,1 17,2 Löwenberg B. FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1 // J. Cell Biol. / J. Nunnari — Rockefeller University Press, 2004. — ISSN 0021-9525; 1540-8140 — doi:10.1083/JCB.200307056 — PMID:14734530
- ↑ 18,0 18,1 18,2 18,3 A Brunet, A Bonni, Zigmond M. J. et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor // Cell — Cell Press, Elsevier, 1999. — ISSN 0092-8674; 1097-4172 — doi:10.1016/S0092-8674(00)80595-4 — PMID:10102273
- ↑ Hung M., Lee D., Xia W. et al. IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a // Cell — Cell Press, Elsevier, 2004. — ISSN 0092-8674; 1097-4172 — doi:10.1016/S0092-8674(04)00302-2 — PMID:15084260
- ↑ Tezil T., Fasano C., Peserico A. et al. Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy // Cell Death Dis. — London: Nature Publishing Group, 2018. — ISSN 2041-4889 — doi:10.1038/S41419-018-0336-0 — PMID:29445193
- ↑ 21,0 21,1 Hung M., Lee D., Xia W. et al. IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a // Cell — Cell Press, Elsevier, 2004. — ISSN 0092-8674; 1097-4172 — doi:10.1016/S0092-8674(04)00302-2 — PMID:15084260
- ↑ Patterson C., Bode C., Augustin H. BMPER is an endothelial cell regulator and controls bone morphogenetic protein-4-dependent angiogenesis // Circ. Res. — Lippincott Williams & Wilkins, 2008. — ISSN 0009-7330; 1524-4571 — doi:10.1161/CIRCRESAHA.108.178434 — PMID:18787191
- ↑ Wang K., Li P. Foxo3a regulates apoptosis by negatively targeting miR-21 // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2010. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M109.093005 — PMID:20371612
- ↑ Hanniford D., Bhardwaj N. Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 2009. — 6 p. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.0808263106 — PMID:19188590
- ↑ Patterson C., Bode C., Augustin H. BMPER is an endothelial cell regulator and controls bone morphogenetic protein-4-dependent angiogenesis // Circ. Res. — Lippincott Williams & Wilkins, 2008. — ISSN 0009-7330; 1524-4571 — doi:10.1161/CIRCRESAHA.108.178434 — PMID:18787191
- ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
- ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.
Чыганаклар
[үзгәртү | вики-текстны үзгәртү]- Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
- Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)
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