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University of The East Ramon Magsaysay Memorial Medical Center Department of Biochemistry QUIZ # 5 NAME: - SECTION A DATE: - Topic: FA Synthesis

This document contains three quiz sections from the Department of Biochemistry at the University of the East Ramon Magsaysay Memorial Medical Center. Each section contains multiple choice questions testing knowledge of fatty acid synthesis, including the enzymes, cofactors, and intracellular locations involved in the process. Key steps assessed include fatty acid elongation, regulation by hormones like insulin and glucagon, and the role of acetyl-CoA carboxylase.

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52 views

University of The East Ramon Magsaysay Memorial Medical Center Department of Biochemistry QUIZ # 5 NAME: - SECTION A DATE: - Topic: FA Synthesis

This document contains three quiz sections from the Department of Biochemistry at the University of the East Ramon Magsaysay Memorial Medical Center. Each section contains multiple choice questions testing knowledge of fatty acid synthesis, including the enzymes, cofactors, and intracellular locations involved in the process. Key steps assessed include fatty acid elongation, regulation by hormones like insulin and glucagon, and the role of acetyl-CoA carboxylase.

Uploaded by

Manila Med
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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UNIVERSITY OF THE EAST

RAMON MAGSAYSAY MEMORIAL MEDICAL CENTER


DEPARTMENT OF BIOCHEMISTRY

QUIZ # 5 NAME : _______________________________ SECTION A DATE: _________


Topic: FA Synthesis
CHOOSE THE LETTER OF THE BEST ANSWER:

46. What is the committed enzyme in lipogenesis?


A. acetyl CoA carboxylase (ACC1) C. HMG CoA synthase (HMGS)
B. malonyl CoA decarboxylase (MCAD) D. HMGCoA reductase (HMGR)

47. What is the biologic effect; covalent modification pair of insulin on ACC1?
A. active: dephosphorylation C. inactive: dephosphorylation
B. active: phosphorylation D. inactive: phosphorylation

48. Which exerts an inhibitory effect on FA oxidation?


A. acetyl CoA carboxylase (ACC1) C. HMG CoA synthase (HMGS)
B. malonyl CoA decarboxylase (MCAD) D. HMGCoA reductase (HMGR)

49. What is the reducing equivalent required in palmitate synthesis?


A. FADH B. NADH C. NADPH

50. What is the biologic effect: covalent modification pair of glucagon on hormone sensitive lipase
(HSL)?
A. active: dephosphorylation C. inactive: dephosphorylation
B. active: phosphorylation D. inactive: phosphorylation

51. Which is the biochemical process resulting from the action of lipoprotein lipase on TAGs?
A. acetylation B. dehydration C. esterification D. hydrolysis

52. Which enzyme will hydrolyze TAGs in the FED state?


A. hormone sensitive lipase B. lipoprotein lipase C. pancreatic lipase

53. Which will transport TAGs from the diet to the liver?
A. chylomicrons B. LDL C. VLDL

54. Which dehydrogenase(DH) enzyme will generate NADPH?


A. a-KG DH B. isocitrate DH C. glucose 6-P DH D. succinyl CoA DH

55. What is the reducing equivalent required for a 10C elongation in the cytoplasm?
A. FADH B. NADH C. NADPH
UNIVERSITY OF THE EAST
RAMON MAGSAYSAY MEMORIAL MEDICAL CENTER
DEPARTMENT OF BIOCHEMISTRY

QUIZ # 5 NAME : _______________________________ SECTION B DATE: _________


Topic: FA Synthesis
CHOOSE THE LETTER OF THE BEST ANSWER:

46. Which intracellular compartment would elongation of a 16 carbon saturated fatty acid occur?
A. cytoplasm B. endoplasmic reticulum C. mitochondria

47. What is the biologic effect; covalent modification pair of glucagon on ACC1?
A. active: dephosphorylation C. inactive: dephosphorylation
B. active: phosphorylation D. inactive: phosphorylation

48. What process will release palmitate from fatty acid synthase (FAS)?
A. decarboxylation B. dehydration C. hydrolysis D. reduction

49. What is the reducing equivalent required for palmitate elongation in the ER?
A. FADH B. NADH C. NADPH

50. What is the biologic effect; covalent modification pair of insulin on hormone sensitive lipase (HSL)?
A. active: dephosphorylation C. inactive: dephosphorylation
B. active: phosphorylation D. inactive: phosphorylation

51. Which is the biochemical process resulting from the action of hormone sensitive lipase on TAGs?
A. acetylation B. dehydration C. esterification D. hydrolysis

52. Which will transport TAGs from the diet to the liver?
A. chylomicrons B. LDL C. VLDL

53. Which enzyme will hydrolyze TAGs in the FED state?


A. hormone sensitive lipase B. lipoprotein lipase C. pancreatic lipase

54. Which dehydrogenase (DH) enzyme will generate NADPH?


A. a-KG DH B. isocitrate DH C. glucose 6-P DH D. succinyl CoA DH

55. What is the reducing equivalent required for a 10C elongation in the cytoplasm?
A. FADH B. NADH C. NADPH
UNIVERSITY OF THE EAST
RAMON MAGSAYSAY MEMORIAL MEDICAL CENTER
DEPARTMENT OF BIOCHEMISTRY

QUIZ # 5 NAME : _______________________________ SECTION C DATE: _________


CHOOSE THE LETTER OF THE BEST ANSWER:
Topic: FA Synthesis
46. Which will donate the 2-carbons in fatty acid elongation in a 16 carbon saturated fatty acid?
A. acetyl CoA B. malonyl CoA C. propionyl CoA

47. What is the biologic effect; covalent modification pair of epinephrine on ACC1?
A. active: dephosphorylation C. inactive: dephosphorylation
B. active: phosphorylation D. inactive: phosphorylation

48. What will be the covalent modification: conformational change on ACC1 in the FED state?
A. phosphorylation: dimerization C. phosphorylation: polymerization
B. dephosphorylation: dimerization D. dephosphorylation: polymerization

49. What is the reducing equivalent required for a 10C elongation in the cytoplasm?
A. FADH B. NADH C. NADPH

50. What is the reducing equivalent required for palmitate elongation in the ER?
A. FADH B. NADH C. NADPH

51. What is the biologic effect: covalent modification pair of epinephrine on hormone sensitive lipase
(HSL)?
A. active: dephosphorylation C. inactive: dephosphorylation
B. active: phosphorylation D. inactive: phosphorylation

52. Which is the biochemical process resulting from the action of non-specific hepatic lipases on TAGs?
A. acetylation B. dehydration C. esterification D. hydrolysis

53. Which dehydrogenase(DH) enzyme will generate NADPH?


A. a-KG DH B. isocitrate DH C. glucose 6-P DH D. succinyl CoA DH

54. What process will release palmitate from fatty acid synthase (FAS)?
A. decarboxylation B. dehydration C. hydrolysis D. reduction

55. Which enzyme will hydrolyze TAGs in the FED state?


A. hormone sensitive lipase B. lipoprotein lipase C. pancreatic lipase

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