Delusional Disorder
Delusional Disorder
People with delusional disorder often can continue to socialize and function quite normally, apart
from the subject of their delusion, and generally do not behave in an obviously odd or bizarre
manner. This is unlike people with other psychotic disorders, who also might have delusions as a
symptom of their disorder. In some cases, however, people with delusional disorder might become
so preoccupied with their delusions that their lives are disrupted.
Grandiose. A person with this type of delusional disorder has an over-inflated sense of
worth, power, knowledge, or identity. The person might believe he or she has a great talent
or has made an important discovery.
Jealous. A person with this type of delusional disorder believes that his or her spouse or
sexual partner is unfaithful.
Persecutory. People with this type of delusional disorder believe that they (or someone
close to them) are being mistreated, or that someone is spying on them or planning to harm
them. It is not uncommon for people with this type of delusional disorder to make repeated
complaints to legal authorities.
Somatic. A person with this type of delusional disorder believes that he or she has a physical
defect or medical problem.
Mixed. People with this type of delusional disorder have two or more of the types of
delusions listed above.
If the doctor finds no physical reason for the symptoms, he or she might refer the person to a
psychiatrist or psychologist, health care professionals who are specially trained to diagnose and treat
mental illnesses. Psychiatrists and psychologists use specially designed interview and assessment
tools to evaluate a person for a psychotic disorder. The doctor or therapist bases his or her diagnosis
on the person’s report of symptoms, and his or her observation of the person’s attitude and
behaviour.
The doctor or therapist then determines if the person’s symptoms point to a specific disorder as
outlined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), which is published by
the American Psychiatric Association and is the standard reference book for recognized mental
illnesses. According to the DSM-5, a diagnosis of delusional disorder is made if a person has non-
bizarre delusions for at least one month and does not have the characteristic symptoms of other
psychotic disorders, such as schizophrenia.
Psychosocial treatments. Various psychosocial treatments can help with the behavioural and
psychological problems associated with delusional disorder. Through therapy, patients also can learn
to control their symptoms, identify early warning signs of relapse, and develop a relapse prevention
plan. Psychosocial therapies include the following:
Individual psychotherapy can help the person recognize and correct the underlying thinking
that has become distorted.
Cognitive-behavioural therapy (CBT) helps the person learn to recognize and change
thought patterns and behaviours that lead to troublesome feelings.
Family therapy can help families deal more effectively with a loved one who has delusional
disorder, enabling them to contribute to a better outcome for the person.
Medications: The primary medications used to attempt to treat delusional disorder are called anti-
psychotics. Medications include the following:
Conventional antipsychotics, also called neuroleptics, have been used to treat mental
disorders since the mid-1950s. These medicines work by blocking dopamine receptors in the
brain. Dopamine is a neurotransmitter believed to be involved in the development of
delusions. Conventional antipsychotics include chlorpromazine (Thorazine®), fluphenazine
(Prolixin®), haloperidol (Haldol®), thiothixene (Navane®), trifluoperazine (Stelazine®),
perphenazine (Trilafon®) and thioridazine (Mellaril®).
Newer medications — called atypical antipsychotic drugs — appear to be more effective in
treating the symptoms of delusional disorder. These medications work by blocking
dopamine and serotonin receptors in the brain. Serotonin is another neurotransmitter
believed to be involved in delusional disorder. These drugs include risperidone (Risperdal®),
clozapine (Clozaril®), quetiapine (Seroquel®), ziprasidone (Geodon®) and olanzapine
(Zyprexa®).
Other medications that might be used to treat delusional disorder include tranquilizers and
antidepressants. Tranquilizers might be used if the person has a very high level of anxiety
and/or problems sleeping. Antidepressants might be used to treat depression, which often
occurs in people with delusional disorder.
PREVENTION
OUTLOOK / PROGNOSIS
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